Metabolic profile and oxidative status in goats during the peripartum period
Pietro Celi A D , Adriana Di Trana B and Angelo Quaranta CA Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia.
B Dipartimento di Scienze delle Produzioni Animali, Università della Basilicata, Italy.
C Dipartimento di Produzione Animale, Università degli Studi di Bari, Italy.
D Corresponding author. Email: pietroc@camden.usyd.edu.au
Australian Journal of Experimental Agriculture 48(7) 1004-1008 https://doi.org/10.1071/EA07410
Submitted: 11 December 2007 Accepted: 21 April 2008 Published: 20 June 2008
Abstract
The aim of this study was to monitor the metabolic profile and oxidative status in goats during the peripartum period. A blood sample was taken from 10 Red Syrian goats on days −21, −3, +1, +14, and +28 from delivery. Samples were assayed for glutathione peroxidase and superoxide dismutase activities, and reactive oxygen metabolites, insulin, insulin-like growth factor-I, free triiodothyronine (fT3), free thyroxine (fT4), leptin, urea, non-esterified fatty acids, triglycerides, cholesterol, total protein, albumin, globulin, calcium and inorganic phosphorus concentrations. Blood glutathione peroxidase activity decreased during the postpartum period and its values were significantly (P < 0.05) lower on days 14 and 28 postpartum. Albumin levels were significantly (P < 0.05) lower on days −3, 1 and 28 from delivery compared with day −21. Plasma urea levels significantly (P < 0.001) decreased starting from day −3 from delivery. No effect of time from delivery was noted on reactive oxygen metabolites, non-esterified fatty acids, triglycerides, cholesterol, total protein, calcium and inorganic phosphorus, insulin and leptin concentrations and superoxide dismutase activity. Plasma concentrations of fT3 were significantly (P < 0.01) higher on days 14 and 28 compared with days −21, −3 and 1 from delivery. Plasma levels of fT4 were significantly (P < 0.01) lower on days −3 and 1 from delivery. Plasma insulin-like growth factor-I values slowly decreased during the postpartum period and its values were significantly (P < 0.05) lower on day 28. This study indicates that goats experienced moderate oxidative stress during the peripartum period.
Acknowledgements
The authors would like to thank Paolo Infantino and Giovanni Masino for their invaluable contribution made during the trial. This research was supported by the Italian Ministry of Education, University and Scientific Research.
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