The Synthesis of Melatonin Antigens
IA Blair and CJ Seaborn
Australian Journal of Chemistry
32(2) 399 - 403
Published: 1979
Abstract
The synthetic strategy required for the development of a radioimmunoassay for the hormone melatonin* is discussed. A facile entry into the N-(1-carboxyalkyl)melatonins (9), (10), (11) is described. The utility of these compounds as versatile haptens for the synthesis of melatonin antigens (12), (13), (14) is demonstrated.
https://doi.org/10.1071/CH9790399
© CSIRO 1979