Synthesis of an arylhydroxytetronimide and of 3-Hydroxy-4(1H)-quinolone derivatives

Abstract

o-(N-Methy1formamido)benzaldehyde reacted with glyoxal bisulphite and sodium cyanide in alkaline solution to yield 2-imino-5-[T-(N-methylformamido)phenyl]-2,5-dihydrofuran-3,4-diol. Under the same reaction conditions o-amino- and o-N-methylamino-benzaldehyde yielded 3-hydroxy-4(1H)- quinolone (quinoline-3,4-diol) and 3-hydroxy-1-methyl-4(1H)-quinolone respectively.