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Australian Journal of Biological Sciences Australian Journal of Biological Sciences Society
Biological Sciences
RESEARCH ARTICLE

Progressive Changes in Plasma Progesterone, Prolactin and Corticosteroid Levels During Late Pregnancy and the Initiation of Lactose Synthesis in the Rat

KR Nicholas and PE Hartmann

Australian Journal of Biological Sciences 34(4) 445 - 454
Published: 1981

Abstract

The relationship between progesterone, prolactin, corticosteroids and corticosteroid binding globulin . (CBO) activity in plasma and the initiation of lactation were studied in normal parturient rats, and rats either ovariohysterectomized or Caesarean-sectioned on day 19 of gestation. In chronically cannulated rats the decline in plasma progesterone to low values « 10 p.g/l) in normal parturient rats 20 h before term and in Caesarean-sectioned rats 10--14 h after surgery was closely related to an increase in plasma prolactin.

https://doi.org/10.1071/BI9810445

© CSIRO 1981

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