Oestradiol and Progesterone: Soluble Receptor Levels and Metabolism in the Uterus of the Ovariectomized Ewe

Abstract

Ovariectomized ewes received injections designed to mimic to some extent oestradiol and progesterone secretion during early pregnancy (maintenance progesterone), during oestrus (oestrous oestradiol) and during the luteal phase of the previous cycle (priming progesterone). The animals were killed at times equivalent to 1, 4 or 7 days after oestrus in those animals which had received oestrous oestradiol. The level of soluble oestradiol and progesterone receptors in whole uterus, and [3Hloestradiol and [3Hlprogesterone metabolism by uterus minces were measured.