Corynetoxins are not detoxicated by in vitro fermentation in ovine rumen fluid

Abstract

Tunicamycin and seed galls of annual ryegrass (Lolium rigidum) containing corynetoxins, the causal agents of annual ryegrass toxicity, were incubated in ovine rumen fluid-buffer mixtures. A bacterial inhibition assay of extracted incubation mixtures revealed that no detoxication occurred under these in vitro conditions.