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Animal Production Science Animal Production Science Society
Food, fibre and pharmaceuticals from animals
REVIEW

Deer antlers: traditional Chinese medicine use and recent pharmaceuticals

Chunyi Li
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Changchun Sci-Tech University, Changchun, China. Email: lichunyi1959@163.com

Animal Production Science 60(10) 1233-1237 https://doi.org/10.1071/AN19168
Submitted: 23 March 2019  Accepted: 29 July 2019   Published: 20 April 2020

Abstract

Deer velvet antlers (VA) have been used as a type of traditional Chinese medicine for over 2000 years, mainly for treating yang-deficiency syndromes. However, VA still largely remain a traditional remedy with scant science, although getting more attention as time goes. In recent years, our group has been trying to develop some efficacious drugs/functional food based on unique biological phenomena of VA, such as, for example, dead tissue (hard antler base) being attached to living tissue (pedicle) for over half a year without causing inflammation, a large-size wound (up to 10 cm in diameter) being left on top of a pedicle stump after previous antler casting healing within a week only with a negligible scar, and severely osteoporotic skeleton caused by intensive antler calcification fully reversing after the completion of antler calcification. Successful translation of these unique phenomena to clinical use would greatly benefit human health.

Additional keywords: animal physiology, animal production.


References

Compston JE, McClung MR, Leslie WD (2019) Osteoporosis. Lancet 393, 364–376.

Goss RJ (1983) ‘Deer antlers. Regeneration, function and evolution.’ (Academic Press: New York, NY, USA)

Kong YC, But PPH (1985) Deer: the ultimate medicinal animal (antler and deer parts in medicine). In ‘Biology of deer production’. Bulletin 22. (Eds PF Fennessy, KR Drew) pp. 311–324. (Royal Society of New Zealand: Wellington, New Zealand)

Li C (2012) Deer antler regeneration: a stem cell-based epimorphic process. Birth Defects Research. Part C, Embryo Today 96, 51–62.
Deer antler regeneration: a stem cell-based epimorphic process.Crossref | GoogleScholarGoogle Scholar | 22457177PubMed |

Li C, Suttie JM, Clark DE (2004) Morphological observation of antler regeneration in red deer (Cervus elaphus). Journal of Morphology 262, 731–740.
Morphological observation of antler regeneration in red deer (Cervus elaphus).Crossref | GoogleScholarGoogle Scholar | 15487018PubMed |

Li C, Suttie JM, Clark DE (2005) Histological examination of antler regeneration in red deer (Cervus elaphus). The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology 282A, 163–174.
Histological examination of antler regeneration in red deer (Cervus elaphus).Crossref | GoogleScholarGoogle Scholar |

Li C, Yang F, Sheppard A (2009) Adult stem cells and mammalian epimorphic regeneration: insights from studying annual renewal of deer antlers. Current Stem Cell Research & Therapy 4, 237–251.
Adult stem cells and mammalian epimorphic regeneration: insights from studying annual renewal of deer antlers.Crossref | GoogleScholarGoogle Scholar |

Li C, Zhao H, Liu Z, McMahon C (2014) Deer antler: a novel model for studying organ regeneration in mammals. The International Journal of Biochemistry & Cell Biology 56, 111–122.
Deer antler: a novel model for studying organ regeneration in mammals.Crossref | GoogleScholarGoogle Scholar |

Rong X, Chu W, Zhang H, Wang Y, Qi X, Zhang G, Wang Y, Chunyi Li (2019) Antler stem cell-conditioned medium stimulates regenerative wound healing in rats Stem Cell Research & Therapy 10, 326
Antler stem cell-conditioned medium stimulates regenerative wound healing in ratsCrossref | GoogleScholarGoogle Scholar |