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RESEARCH ARTICLE
Contents Vol 35(6)

Assessing the suitability of the parasitic nematode Parastrongyloides trichosuri as a vector for transmissible fertility control of brushtail possums in New Zealand – ecological and regulatory considerations

P. E. Cowan A , W. N. Grant B C and M. Ralston B D
+ Author Affiliations
- Author Affiliations

A Landcare Research, PB 11052, Palmerston North 4442, New Zealand.

B AgResearch, PO Box 40063, Upper Hutt, New Zealand.

C Current address: Genetics Department, La Trobe University, Bundoora, Vic. 3086, Australia.

D Current address: 106 Avro Road, Road 1, Upper Hutt, New Zealand.

E Corresponding author. Email: cowanp@landcareresearch.co.nz

Wildlife Research 35(6) 573-577 https://doi.org/10.1071/WR07174
Submitted: 14 November 2007  Accepted: 3 March 2008   Published: 22 October 2008

Abstract

The suitability of the nematode Parastrongyloides trichosuri (Nematoda: Strongyloididae) as a genetically modified vector for transmissible fertility control of introduced brushtail possums (Trichosurus vulpecula) is being explored in New Zealand. This review of progress in assessing the ecological and epidemiological characteristics of P. trichosuri against a set of essential properties for a suitable transmissible vector indicates that the parasite appears to have all the attributes of a highly effective vector, although additional information on persistence at low host density and on the outcome of competition between existing infection and new (recombinant) strains is needed to confirm this. Concerns have been raised about risks to possums and other marsupials in Australia from a genetically modified form of P. trichosuri. An international body with responsibility for managing consultation and debate about issues arising from the proposed use of genetically modified organisms for vertebrate pest management has been suggested as a way of addressing such concerns. A key issue remains as to which agency or group of agencies would take responsibility for such a body. A joint meeting of relevant agencies and researchers is needed urgently to begin the process of moving this issue forward.


Acknowledgements

Roger Pech, Mandy Barron, Dan Tompkins, Janine Duckworth and Lyn Hinds provided helpful comment on the draft manuscript. This publication is an output from the National Research Centre for Possum Biocontrol, and was funded by the Foundation for Research, Science and Technology (Contract 10X0501) and the Animal Health Board.


References

Anderson R. M. , and May R. M. (1991). ‘Infectious Diseases of Humans.’ (Oxford University Press: Oxford.)

Angulo, E. , and Cooke, B. (2002). First synthesize new viruses then regulate their release? The case of the wild rabbit. Molecular Ecology 11, 2703–2709.
| Crossref | GoogleScholarGoogle Scholar | CAS | PubMed | Brockie R. E. , Bell B. D. , and White A. J. (1981). Age structure and mortality of possum Trichosurus vulpecula populations from New Zealand. In ‘Proceedings of the First Symposium on Marsupials in New Zealand’. (Ed. B. D. Bell.) Zoology Publications from Victoria University of Wellington 74, 63–86.

Coleman J. , and Caley P. (2000). Possums as a reservoir of bovine Tb. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 92–104. (Manaaki Whenua Press: Lincoln, New Zealand.)

Cooper, D. W. , and Larsen, E. (2006). Immunocontraception of mammalian wildlife: ecological and immunological issues. Reproduction 132, 821–828.
| Crossref | GoogleScholarGoogle Scholar | CAS | PubMed | Cowan P. (2005). Brushtail possum. In ‘The Handbook of New Zealand Mammals’. 2nd edn. (Ed. C. M. King.) pp. 56–80. (Oxford University Press: Auckland.)

Cowan P. E. (2000). Biological control of possums: prospects for the future. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 263–271. (Manaaki Whenua Press: Lincoln, New Zealand.)

Cowan P. E. , Clark J. M. , Heath D. D. , Stankiewicz M. , and Meers J. (2000). Predators, parasites, and diseases of possums. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 82–91. (Manaaki Whenua Press: Lincoln, New Zealand.)

Cowan, P. E. , Heath, D. D. , and Stankiewicz, M. (2002a). Effects of season, age, and sex on infection with endoparasites of brushtail possums, Trichosurus vulpecula, from a forest/farmland site, lower North Island, New Zealand. New Zealand Journal of Zoology 29, 161–169.
Efford M. G. (2000). Population density, population structure, and dynamics. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 47–61. (Manaaki Whenua Press: Lincoln, New Zealand.)

Fitzgerald G. , Wilkinson W. , and Saunders L. (2000). Public perceptions and issues in possum control. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 189–197. (Manaaki Whenua Press: Lincoln, New Zealand.)

Galloway Maclean, K. (2005). Bridging the gap between researchers and policy-makers: international collaboration through the Biosafety Clearing-House. Environmental Biosafety Research 4, 123–126.
| Crossref | GoogleScholarGoogle Scholar | PubMed | Green W. Q. (1984). A review of ecological studies relevant to management of the common brushtail possum. In ‘Possums and Gliders’. (Eds A. P. Smith and I. D. Hume.) pp. 483–99. (Surrey Beatty: Sydney.)

Hardy C. M. (2007). Current status of virally vectored immunocontraception for biological control of mice. In ‘Gamete Biology: Emerging Frontiers on Fertility and Contraceptive Development’. (Eds S. K. Gupta, K. Koyama, and J. F. Murray.) pp. 495–506. (Nottingham University Press: Nottingham, UK.)

Heath, D. D. , Stankiewicz, M. , Jowett, G. , Flanagan, J. , and Cowan, P. E. (1999). Immunological studies of Parastrongyloides trichosuri (Nematoda) in brushtail possums, Trichosurus vulpecula. Acta Parasitologica 44, 131–136.
Henderson W. , and Murphy E. (2006). International issues and implications of using genetically modified organisms for biocontrol of vertebrate pests. Invasive Animals Cooperative Research Centre, Canberra.

Henzell, R. (2007). Prospects for managing vertebrate pests in Australia with GMO technologies. Agricultural Science 20, 43–47.
Hinds L. A. , Hardy C. M. , and Peacock A. J. (2007). VVIC in Australia: why the research has stopped. In ‘6th International Conference on Fertility Control for Wildlife. 3–5 September 2007. York, UK’. Abstract p.15.

King C. M. (2005). ‘The Handbook of New Zealand Mammals’. 2nd edn. (Oxford University Press: Auckland.)

Magiafoglou, A. , Schiffer, M. , Hoffmann, A. A. , and McKechnie, S. W. (2003). Immunocontraception for population control: will resistance evolve? Immunology and Cell Biology 81, 152–159.
| Crossref | GoogleScholarGoogle Scholar | PubMed | Nugent G. , Whitford J. , Sweetapple P. , and Duncan R. (2007). Intermittent possum control: how long before next time? Changes in possum density, browse pressure, and canopy impacts over 6–8 years after control. Landcare Research Contract Report LC0607/165 for the Department of Conservation.

Nugent G. , Sweetapple P. , Coleman J. , and Suisted P. (2000). Possum feeding patterns: dietary tactics of a reluctant folivore. In ‘The Brushtail Possum. Biology, Impact and Management of an Introduced Marsupial’. (Ed. T. Montague.) pp. 10–23. (Manaaki Whenua Press: Lincoln, New Zealand.)

Parliamentary Commissioner for the Environment (2000). Caught in the headlights. New Zealanders’ reflections on possums, control options and genetic engineering. Wellington, Parliamentary Commissioner for the Environment. Te Kaitiaki Taiao a Te Whare Paremata.

Presidente P. J. A. 1984. Parasites and diseases of brushtail possums (Trichosurus spp.): occurrence and significance. In ‘Possums and Gliders’. (Eds A. Smith and I. Hume.) pp. 171–190. (Surrey Beatty: Sydney.)

Ramsey, D. (2005). Population dynamics of brushtail possums subject to fertility control. Journal of Applied Ecology 42, 348–360.
| Crossref | GoogleScholarGoogle Scholar | Rush J. S. (2001). Management of wildlife populations by immunocontraception. Report commissioned by the Co-operative Research Centre for the Conservation and Management of Marsupials.

Shellam, G. R. (1994). The potential of murine cytomegalovirus as a viral vector for immunocontraception.  Reproduction, Fertility and Development 6, 401–419.
| Crossref | GoogleScholarGoogle Scholar | CAS | Tompkins D. M. , Dobson A. P. , Arneberg P. , Begon M. E. , Cattadori I. M. , et al. (2002). Parasites and host population dynamics. In ‘Ecology of Wildlife Diseases’. (Eds P. J. Hudson, B. T. Grenfell, H. Heesterbeek and A. P. Dobson.) pp. 45–62. (Oxford University Press: Oxford.)

Viggers, K. L. , and Spratt, D. M. (1995). The parasites recorded from Trichosurus species (Marsupialia: Phalangeridae). Wildlife Research 22, 311–332.
| Crossref | GoogleScholarGoogle Scholar | Wilkinson R and Fitzgerald G. (2006). Public attitudes toward possum fertility control and genetic engineering in New Zealand. Landcare Research Science Series No. 29.

Williams, C. K. (2002). Risk assessment for release of genetically modified organisms: a virus to reduce the fertility of introduced wild mice, Mus domesticus. Reproduction Supplement 60, 81–88.
|  CAS |