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Functional Plant Biology Functional Plant Biology Society
Plant function and evolutionary biology
REVIEW

Plant response to heavy metal stress toxicity: the role of metabolomics and other omics tools

K. S. Anjitha A , Nair G. Sarath B , P. P. Sameena C , Edappayil Janeeshma D , A. M. Shackira E and Jos T. Puthur https://orcid.org/0000-0001-5075-3172 A *
+ Author Affiliations
- Author Affiliations

A Plant Physiology and Biochemistry Division, Department of Botany, University of Calicut, C. U. Campus P.O., Malappuram, Kerala 673635, India.

B Department of Botany, Mar Athanasius College, Kothamangalam, Ernakulam, Kerala 686666, India.

C Department of Botany, PSMO College, Tirurangadi, Malappuram, Kerala 676306, India.

D Department of Botany, MES KEVEEYAM College, Valanchery, Malappuram, Kerala 676552, India.

E Department of Botany, Sir Syed College, Kannur University, Kannur, Kerala 670142, India.

* Correspondence to: jtputhur@yahoo.com

Handling Editor: Sergey Shabala

Functional Plant Biology 50(12) 965-982 https://doi.org/10.1071/FP23145
Submitted: 10 July 2023  Accepted: 31 October 2023  Published: 24 November 2023

© 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing

Abstract

Metabolomic investigations offers a significant foundation for improved comprehension of the adaptability of plants to reconfigure the key metabolic pathways and their response to changing climatic conditions. Their application to ecophysiology and ecotoxicology help to assess potential risks caused by the contaminants, their modes of action and the elucidation of metabolic pathways associated with stress responses. Heavy metal stress is one of the most significant environmental hazards affecting the physiological and biochemical processes in plants. Metabolomic tools have been widely utilised in the massive characterisation of the molecular structure of plants at various stages for understanding the diverse aspects of the cellular functioning underlying heavy metal stress-responsive mechanisms. This review emphasises on the recent progressions in metabolomics in plants subjected to heavy metal stresses. Also, it discusses the possibility of facilitating effective management strategies concerning metabolites for mitigating the negative impacts of heavy metal contaminants on the growth and productivity of plants.

Keywords: GC-MS, heavy metal stress, LC-MS, metabolic engineering, metabolomics, NMR spectroscopy, OMICS, stress tolerance.

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