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REVIEW (Open Access)
Contents Vol 36(18)

Reproductive mechanisms, pathologies, and health inclusivity: insights from the 2023 Annual Meeting of the Society for Reproductive Biology

Brendan J. Houston https://orcid.org/0000-0002-1078-756X A * , Hon Y. Chan https://orcid.org/0000-0001-9841-2094 B , Zaramasina Clark https://orcid.org/0000-0002-2942-9447 C , Aleona Swegen D E , Amy L. Wooldridge F and Ella S. Green https://orcid.org/0000-0002-3009-3442 B
+ Author Affiliations
- Author Affiliations

A School of BioSciences, The University of Melbourne, Parkville, Vic, Australia.

B Robinson Research Institute and School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.

C School of Biological Sciences, Te Herenga Waka Victoria University of Wellington, Wellington, New Zealand.

D School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, Australia.

E Infertility and Reproduction Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.

F Robinson Research Institute and School of Biological Sciences, The University of Adelaide, Adelaide, SA, Australia.

* Correspondence to: brendan.houston@unimelb.edu.au

Handling Editor: Graeme Martin

Reproduction, Fertility and Development 36, RD24182 https://doi.org/10.1071/RD24182
Submitted: 1 November 2024  Accepted: 18 November 2024  Published online: 6 December 2024

© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)

Abstract

In 2023, the Society for Reproductive Biology met in Brisbane to deliver its largest scientific program to date. Herein, we detail key areas of notable discovery across the reproductive biology and fertility landscapes, as well as pressing areas that require further research. Specifically, we focus on five key themes: the cellular basis of reproduction; environmental impacts on reproduction; inclusivity in reproductive health; reproductive cancers; and evolution of reproduction mechanisms. Highlights included the utility of organism models, such as using fruit flies to model human genetic disease, and the development of new blastocyst models; the impact of elevated temperature and endocrine-disrupting chemicals on the germline, sex organ development, and fertility in mammals; how we can improve the inclusivity of transgender and Pacific Rainbow+ people in reproductive health; novel insights in reproductive cancer pathogenesis and inhibitor treatments; and the evolution of the sex chromosomes and sex determination across animals. The breadth of topics covered underscores the far-reaching impacts of reproduction and its related processes across life, health, and wellbeing, as well as for food production and the economy.

Keywords: Drosophila, embryo development, endocrine disrupting chemicals, endometrial stem cells, environmental exposure, epigenetics, fertility preservation, heat stress, iBlastoid, inclusive reproductive health, IVF, livestock management practices, per-fluoroalkyl and polyfluoroalkyl substances, reproductive cancer, reproductive evolution, Society for Reproductive Biology, transgender reproductive health.

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