Relationships between placental adiponectin, leptin, visfatin and resistin and birthweight in cattle
Liuhong Shen A * , Yingkun Zhu A * , Jinbang Xiao A , Bolin Qian A , Tao Jiang A , Junliang Deng A , Guangneng Peng A , Shumin Yu A , Suizhong Cao
A C , Zhicai Zuo A , Xiaoping Ma A , Zhijun Zhong A , Zhihua Ren A , Ya Wang A , Ziyao Zhou A , Haifeng Liu A , Xiaolan Zong B and Yanchun Hu A
+ Author Affiliations
- Author Affiliations
A Sichuan Agricultural University, Chengdu Campus, The Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Chengdu, Sichuan, 611130, China.
B Sichuan Agricultural University, Chengdu Campus, Academic Affairs Office, Chengdu, Sichuan, 611130, China.
C Corresponding author. Email: suizhongcao@sicau.edu.cn
Reproduction, Fertility and Development 32(4) 402-408 https://doi.org/10.1071/RD18247
Submitted: 30 July 2018 Accepted: 1 July 2019 Published: 19 November 2019
Abstract
Adipokines can affect intrauterine development while calf birthweight (CBW) is a breeding standard of calves, which reflects the status of fetal intrauterine development. To explore the correlation between placental adipokines and CBW, 54 healthy Chinese Holstein cows were used in the present study. The cows were grouped according to the CBW of their calves. Placentas were collected immediately after delivery and enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction were used to detect the placental expression levels of adiponectin, leptin, visfatin and resistin. Our results show that the mRNA transcription and blood placental content of adiponectin, leptin, visfatin and resistin increased with increasing CBW. The analysis showed that the mRNA transcription levels of placental adiponectin, leptin and resistin were positively correlated with CBW. The mRNA and protein expression levels of adiponectin, leptin and visfatin between the three groups were significantly correlated. Placental resistin mRNA levels correlated positively with adiponectin mRNA, but not leptin or visfatin. The protein expression levels of resistin were significantly positively correlated with those of adiponectin, leptin and visfatin. These results suggest that placental adipokines play important roles in regulating calf intrauterine growth.
Additional keywords: adipokines, calve birth weight, placenta.
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