Recipient of the 2017 IETS Pioneer Award: Prof. Dr. Heiner Niemann

References

Brambrink, T., Wabnitz, P., Halter, R., Klocke, R., Carnwath, J., Kues, W., Wrenzycki, C., Paul, D., and Niemann, H. (2002). Application of cDNA arrays to monitor mRNA profiles in single preimplantation mouse embryos. Biotechniques 33, 376–378, 380, 382–385.

Deshmukh, R. S., Østrup, O., Strejcek, F., Vejlsted, M., Lucas-Hahn, A., Petersen, B., Li, J., Callesen, H., Niemann, H., and Hyttel, P. (2012). Early aberrations in chromatin dynamics in embryos produced under in vitro conditions. Cell. Reprogram. 14, 225–234.

Dieleman, S. J., Hendriksen, P. J., Viuff, D., Thomsen, P. D., Hyttel, P., Knijn, H. M., Wrenzycki, C., Kruip, T. A., Niemann, H., Gadella, B. M., Bevers, M. M., and Vos, P. L. (2002). Effects of in vivo prematuration and in vivo final maturation on developmental capacity and quality of pre-implantation embryos. Theriogenology 57, 5–20.
| Effects of in vivo prematuration and in vivo final maturation on developmental capacity and quality of pre-implantation embryos.Crossref | GoogleScholarGoogle Scholar |

Fischer, K., Kraner-Scheiber, S., Petersen, B., Rieblinger, B., Buermann, A., Flisikowska, T., Flisikowski, K., Christan, S., Edlinger, M., Baars, W., Kurome, M., Zakhartchenko, V., Kessler, B., Plotzki, E., Szczerbal, I., Switonski, M., Denner, J., Wolf, E., Schwinzer, R., Niemann, H., Kind, A., and Schnieke, A. (2016). Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing. Sci. Rep. 6, 29081.
| Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing.Crossref | GoogleScholarGoogle Scholar |

Hauschild, J., Petersen, B., Santiago, Y., Queisser, A. L., Carnwath, J. W., Lucas-Hahn, A., Zhang, L., Meng, X., Gregory, P. D., Schwinzer, R., Cost, G. J., and Niemann, H. (2011). Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proc. Natl. Acad. Sci. USA 108, 12013–12017.
| Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases.Crossref | GoogleScholarGoogle Scholar |

Heinzmann, J., Hansmann, T., Herrmann, D., Wrenzycki, C., Zechner, U., Haaf, T., and Niemann, H. (2011). Epigenetic profile of developmentally important genes in bovine oocytes. Mol. Reprod. Dev. 78, 188–201.
| Epigenetic profile of developmentally important genes in bovine oocytes.Crossref | GoogleScholarGoogle Scholar |

Hinkel, R., Trenkwalder, T., Petersen, B., Husada, W., Gesenhues, F., Lee, S., Hannappel, E., Bock-Marquette, I., Theisen, D., Leitner, L., Boekstegers, P., Cierniewski, C., Müller, O. J., le Noble, F., Adams, R. H., Weinl, C., Nordheim, A., Reichart, B., Weber, C., Olson, E., Posern, G., Deindl, E., Niemann, H., and Kupatt, C. (2014). MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2. Nat. Commun. 5, 3970.
| MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.Crossref | GoogleScholarGoogle Scholar |

Kues, W. A., Carnwath, J. W., and Niemann, H. (2005). From fibroblasts and stem cells: implications for cell therapies and somatic cloning. Reprod. Fertil. Dev. 17, 125–134.
| From fibroblasts and stem cells: implications for cell therapies and somatic cloning.Crossref | GoogleScholarGoogle Scholar |

Kues, W. A., Sudheer, S., Herrmann, D., Carnwath, J. W., Havlicek, V., Besenfelder, U., Lehrach, H., Adjaye, J., and Niemann, H. (2008). Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo. Proc. Natl. Acad. Sci. USA 105, 19768–19773.
| Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo.Crossref | GoogleScholarGoogle Scholar |

Lazzari, G., Wrenzycki, C., Herrmann, D., Duchi, R., Kruip, T., Niemann, H., and Galli, C. (2002). Cellular and molecular deviations in bovine in vitro-produced embryos are related to the large offspring syndrome. Biol. Reprod. 67, 767–775.
| Cellular and molecular deviations in bovine in vitro-produced embryos are related to the large offspring syndrome.Crossref | GoogleScholarGoogle Scholar |

Niemann, H. (1991). Cryopreservation of ova and embryos from livestock: Current status and research needs. Theriogenology 35, 109–124.
| Cryopreservation of ova and embryos from livestock: Current status and research needs.Crossref | GoogleScholarGoogle Scholar |

Niemann, H., and Elsaesser, F. (1984). Uptake and effects of ovarian steroids in the early pig embryo: In vitro and in vivo studies. Theriogenology 21, 84–102.
| Uptake and effects of ovarian steroids in the early pig embryo: In vitro and in vivo studies.Crossref | GoogleScholarGoogle Scholar |

Niemann, H., and Lucas-Hahn, A. (2012). Somatic cell nuclear transfer cloning: practical applications and current legislation. Reprod. Domest. Anim. 47, 2–10.
| Somatic cell nuclear transfer cloning: practical applications and current legislation.Crossref | GoogleScholarGoogle Scholar |

Niemann, H., and Petersen, B. (2016). The production of multi-transgenic pigs: update and perspectives for xenotransplantation. Transgenic Res. 25, 361–374.
| The production of multi-transgenic pigs: update and perspectives for xenotransplantation.Crossref | GoogleScholarGoogle Scholar |

Niemann, H., and Wrenzycki, C. (2000). Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent development. Theriogenology 53, 21–34.
| Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent development.Crossref | GoogleScholarGoogle Scholar |

Niemann, H., Halter, R., Carnwath, J. W., Herrmann, D., Lemme, E., and Paul, D. (1999). Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep. Transgenic Res. 8, 237–247.
| Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep.Crossref | GoogleScholarGoogle Scholar |

Nowak-Imialek, M., and Niemann, H. (2013). Pluripotent cells in farm animals: state of the art and future perspectives. Reprod. Fertil. Dev. 25, 103–128.
| Pluripotent cells in farm animals: state of the art and future perspectives.Crossref | GoogleScholarGoogle Scholar |

Petersen, B., Frenzel, A., Lucas-Hahn, A., Herrmann, D., Hassel, P., Klein, S., Ziegler, M., Hadeler, K. G., and Niemann, H. (2016). Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes. Xenotransplantation 23, 338–346.
| Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes.Crossref | GoogleScholarGoogle Scholar |

Schaetzlein, S., Lucas-Hahn, A., Lemme, E., Kues, W. A., Dorsch, M., Manns, M. P., Niemann, H., and Rudolph, K. L. (2004). Telomere length is reset during early mammalian embryogenesis. Proc. Natl. Acad. Sci. USA 101, 8034–8038.
| Telomere length is reset during early mammalian embryogenesis.Crossref | GoogleScholarGoogle Scholar |

Wrenzycki, C., and Niemann, H. (2003). Epigenetic reprogramming in early embryonic development: effects of in-vitro production and somatic nuclear transfer. Reprod. Biomed. Online 7, 649–656.
| Epigenetic reprogramming in early embryonic development: effects of in-vitro production and somatic nuclear transfer.Crossref | GoogleScholarGoogle Scholar |

Wrenzycki, C., Herrmann, D., Carnwath, J. W., and Niemann, H. (1996). Expression of the gap junction gene connexin43 (Cx43) in preimplantation bovine embryos derived in vitro or in vivo. J. Reprod. Fertil. 108, 17–24.
| Expression of the gap junction gene connexin43 (Cx43) in preimplantation bovine embryos derived in vitro or in vivo.Crossref | GoogleScholarGoogle Scholar |

Wrenzycki, C., Herrmann, D., Lucas-Hahn, A., Korsawe, K., Lemme, E., and Niemann, H. (2005). Messenger RNA expression patterns in bovine embryos derived from in vitro procedures and their implications for development. Reprod. Fertil. Dev. 17, 23–35.
| Messenger RNA expression patterns in bovine embryos derived from in vitro procedures and their implications for development.Crossref | GoogleScholarGoogle Scholar |