Hosting the preimplantation embryo: potentials and limitations of different approaches for analysing embryo–endometrium interactions in cattle
Susanne E. Ulbrich A C , Eckhard Wolf B and Stefan Bauersachs B
+ Author Affiliations
- Author Affiliations
A Physiology Weihenstephan, Technische Universitaet Muenchen, Weihenstephaner Berg 3, 85354 Freising, Germany.
B Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, Ludwig-Maximilians-Universitaet Muenchen, Feodor-Lynen-Str. 25, 81377 Munich, Germany.
C Corresponding author. Email: ulbrich@wzw.tum.de
Reproduction, Fertility and Development 25(1) 62-70 https://doi.org/10.1071/RD12279
Published: 4 December 2012
Abstract
Ongoing detailed investigations into embryo–maternal communication before implantation reveal that during early embryonic development a plethora of events are taking place. During the sexual cycle, remodelling and differentiation processes in the endometrium are controlled by ovarian hormones, mainly progesterone, to provide a suitable environment for establishment of pregnancy. In addition, embryonic signalling molecules initiate further sequences of events; of these molecules, prostaglandins are discussed herein as specifically important. Inadequate receptivity may impede preimplantation development and implantation, leading to embryonic losses. Because there are multiple factors affecting fertility, receptivity is difficult to comprehend. This review addresses different models and methods that are currently used and discusses their respective potentials and limitations in distinguishing key messages out of molecular twitter. Transcriptome, proteome and metabolome analyses generate comprehensive information and provide starting points for hypotheses, which need to be substantiated using further confirmatory methods. Appropriate in vivo and in vitro models are needed to disentangle the effects of participating factors in the embryo–maternal dialogue and to help distinguish associations from causalities. One interesting model is the study of somatic cell nuclear transfer embryos in normal recipient heifers. A multidisciplinary approach is needed to properly assess the importance of the uterine milieu for embryonic development and to use the large number of new findings to solve long-standing issues regarding fertility.
Additional keywords : somatic cell nuclear transfer, transcriptomics, prostaglandins, uterus.
References
Arnold, G. J., and Frohlich, T. (2011). Dynamic proteome signatures in gametes, embryos and their maternal environment. Reprod. Fertil. Dev. 23, 81–93.| Dynamic proteome signatures in gametes, embryos and their maternal environment.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhvVyqsLc%3D&md5=8acd8330a5ae0296c7848638aecffae0CAS |
Arosh, J. A., Banu, S. K., Chapdelaine, P., Emond, V., Kim, J. J., MacLaren, L. A., and Fortier, M. A. (2003). Molecular cloning and characterization of bovine prostaglandin E2 receptors EP2 and EP4: expression and regulation in endometrium and myometrium during the estrous cycle and early pregnancy. Endocrinology 144, 3076–3091.
| Molecular cloning and characterization of bovine prostaglandin E2 receptors EP2 and EP4: expression and regulation in endometrium and myometrium during the estrous cycle and early pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXkvF2ktL8%3D&md5=4b49a4a74f2217513e8dba795166d47aCAS |
Arosh, J. A., Banu, S. K., Kimmins, S., Chapdelaine, P., MacLaren, L. A., and Fortier, M. A. (2004). Effect of interferon-tau on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of prostaglandin E2. Endocrinology 145, 5280–5293.
| Effect of interferon-tau on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of prostaglandin E2.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2cXptVygsrg%3D&md5=b25216baf601981f9672ffae64be6b83CAS |
Asselin, E., Bazer, F. W., and Fortier, M. A. (1997a). Recombinant ovine and bovine interferons tau regulate prostaglandin production and oxytocin response in cultured bovine endometrial cells. Biol. Reprod. 56, 402–408.
| Recombinant ovine and bovine interferons tau regulate prostaglandin production and oxytocin response in cultured bovine endometrial cells.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK2sXosF2qsw%3D%3D&md5=1bee31a24febd4ec74db5062a3a67d2aCAS |
Asselin, E., Lacroix, D., and Fortier, M. A. (1997b). IFN-tau increases PGE2 production and COX-2 gene expression in the bovine endometrium in vitro. Mol. Cell. Endocrinol. 132, 117–126.
| IFN-tau increases PGE2 production and COX-2 gene expression in the bovine endometrium in vitro.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK2sXlslCjt78%3D&md5=02988dcb2528a531890f96ab4fee3cc3CAS |
Banu, S. K., Arosh, J. A., Chapdelaine, P., and Fortier, M. A. (2003). Molecular cloning and spatio-temporal expression of the prostaglandin transporter: a basis for the action of prostaglandins in the bovine reproductive system. Proc. Natl Acad. Sci. USA 100, 11 747–11 752.
| Molecular cloning and spatio-temporal expression of the prostaglandin transporter: a basis for the action of prostaglandins in the bovine reproductive system.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXotFKmur4%3D&md5=00068437ff3e6f9bfbe7fb18a5faca80CAS |
Bartol, F. F., Thatcher, W. W., Bazer, F. W., Kimball, F. A., Chenault, J. R., Wilcox, C. J., and Roberts, R. M. (1981). Effects of the estrous cycle and early pregnancy on bovine uterine, luteal, and follicular responses. Biol. Reprod. 25, 759–776.
| Effects of the estrous cycle and early pregnancy on bovine uterine, luteal, and follicular responses.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaL38XhtVyq&md5=a1c226dcae3b79d436acd3e82caff8b4CAS |
Batchelder, C. A., Hoffert, K. A., Bertolini, M., Moyer, A. L., Mason, J. B., Petkov, S. G., Famula, T. R., and Anderson, G. B. (2005). Effect of the nuclear-donor cell lineage, type, and cell donor on development of somatic cell nuclear transfer embryos in cattle. Cloning Stem Cells 7, 238–254.
| Effect of the nuclear-donor cell lineage, type, and cell donor on development of somatic cell nuclear transfer embryos in cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xmt1Kh&md5=ca869f7b785784ca4c582b2e44341b63CAS |
Bauersachs, S., and Wolf, E. (2012). Transcriptome analyses of bovine, porcine and equine endometrium during the pre-implantation phase. Anim. Reprod. Sci. 134, 84–94.
| Transcriptome analyses of bovine, porcine and equine endometrium during the pre-implantation phase.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38Xht1ekurrP&md5=64c8a415d22d8f40a9f0c5ba677bce87CAS |
Bauersachs, S., Ulbrich, S. E., Gross, K., Schmidt, S. E., Meyer, H. H., Einspanier, R., Wenigerkind, H., Vermehren, M., Blum, H., Sinowatz, F., and Wolf, E. (2005). Gene expression profiling of bovine endometrium during the oestrous cycle: detection of molecular pathways involved in functional changes. J. Mol. Endocrinol. 34, 889–908.
| Gene expression profiling of bovine endometrium during the oestrous cycle: detection of molecular pathways involved in functional changes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXlslCisL8%3D&md5=cceab8f8aef7b2ca36996e038be2a550CAS |
Bauersachs, S., Ulbrich, S. E., Gross, K., Schmidt, S. E., Meyer, H. H., Wenigerkind, H., Vermehren, M., Sinowatz, F., Blum, H., and Wolf, E. (2006). Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity. Reproduction 132, 319–331.
| Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xpt1Wjs7s%3D&md5=efa9072c02db4c06655ab95d7e048817CAS |
Bauersachs, S., Mitko, K., Ulbrich, S. E., Blum, H., and Wolf, E. (2008). Transcriptome studies of bovine endometrium reveal molecular profiles characteristic for specific stages of estrous cycle and early pregnancy. Exp. Clin. Endocrinol. Diabetes 116, 371–384.
| Transcriptome studies of bovine endometrium reveal molecular profiles characteristic for specific stages of estrous cycle and early pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXht1SgtbzK&md5=b85d631d8c019db2759e96cd3af17d3aCAS |
Bauersachs, S., Ulbrich, S. E., Zakhartchenko, V., Minten, M., Reichenbach, M., Reichenbach, H. D., Blum, H., Spencer, T. E., and Wolf, E. (2009). The endometrium responds differently to cloned versus fertilized embryos. Proc. Natl Acad. Sci. USA 106, 5681–5686.
| The endometrium responds differently to cloned versus fertilized embryos.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXkvFGhurk%3D&md5=051e04fdc18c3748867ca4da6a783b7bCAS |
Bauersachs, S., Ulbrich, S. E., Reichenbach, H. D., Reichenbach, M., Buttner, M., Meyer, H. H., Spencer, T. E., Minten, M., Sax, G., Winter, G., and Wolf, E. (2012). Comparison of the effects of early pregnancy with human interferon, alpha 2 (IFNA2), on gene expression in bovine endometrium. Biol. Reprod. 86, 46.
| Comparison of the effects of early pregnancy with human interferon, alpha 2 (IFNA2), on gene expression in bovine endometrium.Crossref | GoogleScholarGoogle Scholar |
Bazer, F. W., and Slayden, O. D. (2008). Progesterone-induced gene expression in uterine epithelia: a myth perpetuated by conventional wisdom. Biol. Reprod. 79, 1008–1009.
| Progesterone-induced gene expression in uterine epithelia: a myth perpetuated by conventional wisdom.Crossref | GoogleScholarGoogle Scholar |
Bazer, F. W., Spencer, T. E., and Ott, T. L. (1997). Interferon tau: a novel pregnancy recognition signal. Am. J. Reprod. Immunol. 37, 412–420.
| Interferon tau: a novel pregnancy recognition signal.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK2sznt1Sgsw%3D%3D&md5=c7deda1123d636f70e657c90b024c2d0CAS |
Bazer, F. W., Spencer, T. E., and Johnson, G. A. (2009). Interferons and uterine receptivity. Semin. Reprod. Med. 27, 90–102.
| Interferons and uterine receptivity.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhvVGntrY%3D&md5=ce6e5f9f89d2a5b754cdfa97ab3e9fb7CAS |
Bazer, F. W., Spencer, T. E., Johnson, G. A., and Burghardt, R. C. (2011). Uterine receptivity to implantation of blastocysts in mammals. Front Biosci. 3, 745–767.
| Uterine receptivity to implantation of blastocysts in mammals.Crossref | GoogleScholarGoogle Scholar |
Berendt, F. J., Frohlich, T., Schmidt, S. E., Reichenbach, H. D., Wolf, E., and Arnold, G. J. (2005). Holistic differential analysis of embryo-induced alterations in the proteome of bovine endometrium in the preattachment period. Proteomics 5, 2551–2560.
| Holistic differential analysis of embryo-induced alterations in the proteome of bovine endometrium in the preattachment period.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXmtF2gt7k%3D&md5=a12119a45bd93780eba41bf92b3bc47bCAS |
Carter, F., Rings, F., Mamo, S., Holker, M., Kuzmany, A., Besenfelder, U., Havlicek, V., Mehta, J. P., Tesfaye, D., Schellander, K., and Lonergan, P. (2010). Effect of elevated circulating progesterone concentration on bovine blastocyst development and global transcriptome following endoscopic transfer of in vitro produced embryos to the bovine oviduct. Biol. Reprod. 83, 707–719.
| Effect of elevated circulating progesterone concentration on bovine blastocyst development and global transcriptome following endoscopic transfer of in vitro produced embryos to the bovine oviduct.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXhtlGlsrfF&md5=02c288d2e33afbaafd7364d18813a6f6CAS |
Chavatte-Palmer, P., Camous, S., Jammes, H., Le, C. N., Guillomot, M., and Lee, R. S. (2012). Review: placental perturbations induce the developmental abnormalities often observed in bovine somatic cell nuclear transfer. Placenta 33, S99–S104.
| Review: placental perturbations induce the developmental abnormalities often observed in bovine somatic cell nuclear transfer.Crossref | GoogleScholarGoogle Scholar |
Chawla-Sarkar, M., Lindner, D. J., Liu, Y. F., Williams, B. R., Sen, G. C., Silverman, R. H., and Borden, E. C. (2003). Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 8, 237–249.
| Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXjsF2nt70%3D&md5=64a5689ac8bd95fae36e662962f3deacCAS |
Chen, Y., Green, J. A., Antoniou, E., Ealy, A. D., Mathialagan, N., Walker, A. M., Avalle, M. P., Rosenfeld, C. S., Hearne, L. B., and Roberts, R. M. (2006). Effect of interferon-tau administration on endometrium of nonpregnant ewes: a comparison with pregnant ewes. Endocrinology 147, 2127–2137.
| Effect of interferon-tau administration on endometrium of nonpregnant ewes: a comparison with pregnant ewes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XjvFOrtb8%3D&md5=38eaeb162ecd5ca87aa77e780f22f206CAS |
Choi, Y., Johnson, G. A., Burghardt, R. C., Berghman, L. R., Joyce, M. M., Taylor, K. M., Stewart, M. D., Bazer, F. W., and Spencer, T. E. (2001). Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus. Biol. Reprod. 65, 1038–1049.
| Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXnt1Cmsr0%3D&md5=793d2cc1e58394dd4910395ae6f928e2CAS |
Clemente, M., Lopez-Vidriero, I., O’Gaora, P., Mehta, J. P., Forde, N., Gutierrez-Adan, A., Lonergan, P., and Rizos, D. (2011). Transcriptome changes at the initiation of elongation in the bovine conceptus. Biol. Reprod. 85, 285–295.
| Transcriptome changes at the initiation of elongation in the bovine conceptus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXpslOnurg%3D&md5=0059e68c81f85645ee1774d2022a4f41CAS |
Cross, J. C., and Roberts, R. M. (1991). Constitutive and trophoblast-specific expression of a class of bovine interferon genes. Proc. Natl Acad. Sci. USA 88, 3817–3821.
| Constitutive and trophoblast-specific expression of a class of bovine interferon genes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK3MXktVKksrY%3D&md5=498bdbb5f59ec03b927714c82e77d131CAS |
Dean, W., Santos, F., Stojkovic, M., Zakhartchenko, V., Walter, J., Wolf, E., and Reik, W. (2001). Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc. Natl Acad. Sci. USA 98, 13 734–13 738.
| Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXovVyntrs%3D&md5=ec1ab6aba3ad6e5c6d722e32ade6a556CAS |
Dorniak, P., Bazer, F. W., and Spencer, T. E. (2011). Prostaglandins regulate conceptus elongation and mediate effects of interferon tau on the ovine uterine endometrium. Biol. Reprod. 84, 1119–1127.
| Prostaglandins regulate conceptus elongation and mediate effects of interferon tau on the ovine uterine endometrium.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXmvFemur4%3D&md5=8ade31fe4a042008cf47fcaf6ab9b02bCAS |
Dorniak, P., Bazer, F. W., Wu, G., and Spencer, T. E. (2012a). Conceptus-derived prostaglandins regulate endometrial function in sheep. Biol. Reprod. 87, 9.
| Conceptus-derived prostaglandins regulate endometrial function in sheep.Crossref | GoogleScholarGoogle Scholar |
Dorniak, P., and Welsh, T. H. Dorniak, P., and Welsh, T. H. (2012b). Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins. Biol. Reprod. 86, 124.
| Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins.Crossref | GoogleScholarGoogle Scholar |
Ealy, A. D., and Yang, Q. E. (2009). Control of interferon-tau expression during early pregnancy in ruminants. Am. J. Reprod. Immunol. 61, 95–106.
| Control of interferon-tau expression during early pregnancy in ruminants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXislOhu7s%3D&md5=af24ee1da30969154aed6162ba4e182dCAS |
Ellinwood, W. E., Nett, T. M., and Niswender, G. D. (1979). Maintenance of the corpus luteum of early pregnancy in the ewe. II. Prostaglandin secretion by the endometrium in vitro and in vivo. Biol. Reprod. 21, 845–856.
| Maintenance of the corpus luteum of early pregnancy in the ewe. II. Prostaglandin secretion by the endometrium in vitro and in vivo.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaL3cXlsF2ntQ%3D%3D&md5=a93c593061d369b1b0581dcd2ecade13CAS |
Elsik, C. G., Tellam, R. L., Worley, K. C., Gibbs, R. A., Muzny, D. M., Weinstock, G. M., Adelson, D. L., Eichler, E. E., Elnitski, L., Guigo, R., et al. (2009). The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science 324, 522–528.
| The genome sequence of taurine cattle: a window to ruminant biology and evolution.Crossref | GoogleScholarGoogle Scholar |
Emond, V., MacLaren, L. A., Kimmins, S., Arosh, J. A., Fortier, M. A., and Lambert, R. D. (2004). Expression of cyclooxygenase-2 and granulocyte–macrophage colony-stimulating factor in the endometrial epithelium of the cow is up-regulated during early pregnancy and in response to intrauterine infusions of interferon-tau. Biol. Reprod. 70, 54–64.
| Expression of cyclooxygenase-2 and granulocyte–macrophage colony-stimulating factor in the endometrial epithelium of the cow is up-regulated during early pregnancy and in response to intrauterine infusions of interferon-tau.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2cXhvVyh&md5=86ba275255e3c92212ba2baec61dac5eCAS |
Farin, C. E., Imakawa, K., Hansen, T. R., McDonnell, J. J., Murphy, C. N., Farin, P. W., and Roberts, R. M. (1990). Expression of trophoblastic interferon genes in sheep and cattle. Biol. Reprod. 43, 210–218.
| Expression of trophoblastic interferon genes in sheep and cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK3cXkvFGqsbg%3D&md5=90d23f139ce02b5f2761542b45736d13CAS |
Fazeli, A., and Pewsey, E. (2008). Maternal communication with gametes and embryos: a complex interactome. Brief Funct. Genomics Proteomics 7, 111–118.
| Maternal communication with gametes and embryos: a complex interactome.Crossref | GoogleScholarGoogle Scholar |
Fleming, J. G., Spencer, T. E., Safe, S. H., and Bazer, F. W. (2006). Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements. Endocrinology 147, 899–911.
| Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XpvVejsw%3D%3D&md5=dd608b6e0ea6a9f2bd9acba1de1fccccCAS |
Fleming, T. P., Kwong, W. Y., Porter, R., Ursell, E., Fesenko, I., Wilkins, A., Miller, D. J., Watkins, A. J., and Eckert, J. J. (2004). The embryo and its future. Biol. Reprod. 71, 1046–1054.
| The embryo and its future.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2cXnvVGqtrg%3D&md5=af76a12c907c06ad58c637ed0bbf6ea1CAS |
Ford, S. P., Chenault, J. R., and Echternkamp, S. E. (1979). Uterine blood flow of cows during the oestrous cycle and early pregnancy: effect of the conceptus on the uterine blood supply. J. Reprod. Fertil. 56, 53–62.
| Uterine blood flow of cows during the oestrous cycle and early pregnancy: effect of the conceptus on the uterine blood supply.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaE1MXksFemu7s%3D&md5=6fe3abc4f4a991b6aec4ba95fc5da865CAS |
Forde, N., and Lonergan, P. (2012). Transcriptomic analysis of the bovine endometrium: what is required to establish uterine receptivity to implantation in cattle? J. Reprod. Dev. 58, 189–195.
| Transcriptomic analysis of the bovine endometrium: what is required to establish uterine receptivity to implantation in cattle?Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XptVKju7Y%3D&md5=a87500e5c4dd1d2a2be1ccda80edfe3dCAS |
Forde, N., Carter, F., Fair, T., Crowe, M. A., Evans, A. C., Spencer, T. E., Bazer, F. W., McBride, R., Boland, M. P., O’Gaora, P., Lonergan, P., and Roche, J. F. (2009). Progesterone-regulated changes in endometrial gene expression contribute to advanced conceptus development in cattle. Biol. Reprod. 81, 784–794.
| Progesterone-regulated changes in endometrial gene expression contribute to advanced conceptus development in cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhtFyhsLbM&md5=53fdf8f291be12fbedb5d7b8282e6ba4CAS |
Forde, N., Beltman, M. E., Duffy, G. B., Duffy, P., Mehta, J. P., O’Gaora, P., Roche, J. F., Lonergan, P., and Crowe, M. A. (2011a). Changes in the endometrial transcriptome during the bovine estrous cycle: effect of low circulating progesterone and consequences for conceptus elongation. Biol. Reprod. 84, 266–278.
| Changes in the endometrial transcriptome during the bovine estrous cycle: effect of low circulating progesterone and consequences for conceptus elongation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhsVeltr4%3D&md5=3de1ebecae0ad7e03c3c954cf41bbebbCAS |
Forde, N., Carter, F., Spencer, T. E., Bazer, F. W., Sandra, O., Mansouri-Attia, N., Okumu, L. A., McGettigan, P. A., Mehta, J. P., McBride, R., O’Gaora, P., Roche, J. F., and Lonergan, P. (2011b). Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant? Biol. Reprod. 85, 144–156.
| Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant?Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXotFOlsL4%3D&md5=a2cf07cbd83b8718095708fb15073c45CAS |
Forde, N., Duffy, G. B., McGettigan, P. A., Browne, J. A., Prakash, M. J., Kelly, A. K., Mansouri-Attia, N., Sandra, O., Loftus, B. J., Crowe, M. A., Fair, T., Roche, J. F., Lonergan, P., and Evans, A. C. (2012). Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau. Physiol. Genomics 44, 799–810.
| Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC38jmvFKlug%3D%3D&md5=596ab8ab139f91f92e8013497a1a8097CAS |
Gao, H., Wu, G., Spencer, T. E., Johnson, G. A., Li, X., and Bazer, F. W. (2009). Select nutrients in the ovine uterine lumen. I. Amino acids, glucose, and ions in uterine lumenal flushings of cyclic and pregnant ewes. Biol. Reprod. 80, 86–93.
| Select nutrients in the ovine uterine lumen. I. Amino acids, glucose, and ions in uterine lumenal flushings of cyclic and pregnant ewes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXosFOg&md5=39bf2f5165db98a10d890ca5a9b0b8a4CAS |
Gardner, D. S., Ozanne, S. E., and Sinclair, K. D. (2009). Effect of the early-life nutritional environment on fecundity and fertility of mammals. Philos. Trans. R. Soc. Lond. B Biol. Sci. 364, 3419–3427.
| Effect of the early-life nutritional environment on fecundity and fertility of mammals.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD1MnpsFalsA%3D%3D&md5=9dd671376aaece276bde0ec464aaa594CAS |
Godkin, J. D., Smith, S. E., Johnson, R. D., and Dore, J. J. (1997). The role of trophoblast interferons in the maintenance of early pregnancy in ruminants. Am. J. Reprod. Immunol. 37, 137–143.
| The role of trophoblast interferons in the maintenance of early pregnancy in ruminants.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK2s3gsFKruw%3D%3D&md5=31d3494093fc0f59b7ac951af887875aCAS |
Godkin, J. D., Roberts, M. P., Elgayyar, M., Guan, W., and Tithof, P. K. (2008). Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production. Reprod. Biol. Endocrinol. 6, 44.
| Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production.Crossref | GoogleScholarGoogle Scholar |
Gray, C. A., Taylor, K. M., Ramsey, W. S., Hill, J. R., Bazer, F. W., Bartol, F. F., and Spencer, T. E. (2001). Endometrial glands are required for preimplantation conceptus elongation and survival. Biol. Reprod. 64, 1608–1613.
| Endometrial glands are required for preimplantation conceptus elongation and survival.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXjvFGgsbs%3D&md5=8b1ec6378c7f24b3fcf682d11d9d1b3cCAS |
Gray, C. A., Abbey, C. A., Beremand, P. D., Choi, Y., Farmer, J. L., Adelson, D. L., Thomas, T. L., Bazer, F. W., and Spencer, T. E. (2006). Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus. Biol. Reprod. 74, 383–394.
| Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xot1Kktg%3D%3D&md5=e2470ddfb2055e1ab0b71731fa46651bCAS |
Groebner, A. E., Schulke, K., Unterseer, S., Reichenbach, H. D., Reichenbach, M., Buttner, M., Wolf, E., Meyer, H. H., and Ulbrich, S. E. (2010). Enhanced proapoptotic gene expression of XAF1, CASP8 and TNFSF10 in the bovine endometrium during early pregnancy is not correlated with augmented apoptosis. Placenta 31, 168–177.
| Enhanced proapoptotic gene expression of XAF1, CASP8 and TNFSF10 in the bovine endometrium during early pregnancy is not correlated with augmented apoptosis.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXit1Khsrw%3D&md5=884148761dbe00038e20f4d97e3fb21cCAS |
Groebner, A. E., Rubio-Aliaga, I., Schulke, K., Reichenbach, H. D., Daniel, H., Wolf, E., Meyer, H. H., and Ulbrich, S. E. (2011a). Increase of essential amino acids in the bovine uterine lumen during preimplantation development. Reproduction 141, 685–695.
| Increase of essential amino acids in the bovine uterine lumen during preimplantation development.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXmvFCis74%3D&md5=5fbfcf5c19c529332a5b3eac42740f65CAS |
Groebner, A. E., Schulke, K., Schefold, J. C., Fusch, G., Sinowatz, F., Reichenbach, H. D., Wolf, E., Meyer, H. H., and Ulbrich, S. E. (2011b). Immunological mechanisms to establish embryo tolerance in early bovine pregnancy. Reprod. Fertil. Dev. 23, 619–632.
| Immunological mechanisms to establish embryo tolerance in early bovine pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXpvVWqur4%3D&md5=7e5d9ab15c80f1da1ef2221ba09233efCAS |
Groebner, A. E., Zakhartchenko, V., Bauersachs, S., Rubio-Aliaga, I., Daniel, H., Buttner, M., Reichenbach, H. D., Meyer, H. H., Wolf, E., and Ulbrich, S. E. (2011c). Reduced amino acids in the bovine uterine lumen of cloned versus in vitro fertilized pregnancies prior to implantation. Cell. Reprogram. 13, 403–410.
| 1:CAS:528:DC%2BC3MXhtlCgt73F&md5=a8263b5a60b188058c601d82e95ef5e1CAS |
Guzeloglu, A., Michel, F., and Thatcher, W. W. (2004). Differential effects of interferon-tau on the prostaglandin synthetic pathway in bovine endometrial cells treated with phorbol ester. J. Dairy Sci. 87, 2032–2041.
| Differential effects of interferon-tau on the prostaglandin synthetic pathway in bovine endometrial cells treated with phorbol ester.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2cXlvFKltLk%3D&md5=a4a21371a73fac18f2069def9cd54848CAS |
Hales, C. N., and Barker, D. J. (2001). The thrifty phenotype hypothesis. Br. Med. Bull. 60, 5–20.
| The thrifty phenotype hypothesis.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD38%2Fot12mug%3D%3D&md5=ef4835d4430492207fa8f956b5867b89CAS |
Han, C. S., Mathialagan, N., Klemann, S. W., and Roberts, R. M. (1997). Molecular cloning of ovine and bovine Type I interferon receptor subunits from uteri, and endometrial expression of messenger ribonucleic acid for ovine receptors during the estrous cycle and pregnancy. Endocrinology 138, 4757–4767.
| Molecular cloning of ovine and bovine Type I interferon receptor subunits from uteri, and endometrial expression of messenger ribonucleic acid for ovine receptors during the estrous cycle and pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK2sXmslGrt7o%3D&md5=b0b8c54798dbd20478987f5f68a1dedcCAS |
Hansen, P. J. (2011). The immunology of early pregnancy in farm animals. Reprod. Domest. Anim. 46, 18–30.
Heyman, Y., Chavatte-Palmer, P., LeBourhis, D., Camous, S., Vignon, X., and Renard, J. P. (2002). Frequency and occurrence of late-gestation losses from cattle cloned embryos. Biol. Reprod. 66, 6–13.
| Frequency and occurrence of late-gestation losses from cattle cloned embryos.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38Xht1ymug%3D%3D&md5=c5ed8c5607664771f4a372f351646027CAS |
Hill, J. R., Burghardt, R. C., Jones, K., Long, C. R., Looney, C. R., Shin, T., Spencer, T. E., Thompson, J. A., Winger, Q. A., and Westhusin, M. E. (2000). Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses. Biol. Reprod. 63, 1787–1794.
| Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3cXosVKhtL4%3D&md5=c82ba70f2ea7757f0d03b5b2f369fe71CAS |
Hugentobler, S. A., Humpherson, P. G., Leese, H. J., Sreenan, J. M., and Morris, D. G. (2008). Energy substrates in bovine oviduct and uterine fluid and blood plasma during the oestrous cycle. Mol. Reprod. Dev. 75, 496–503.
| Energy substrates in bovine oviduct and uterine fluid and blood plasma during the oestrous cycle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhs1Crsrw%3D&md5=1c0703aa3b3c5f9034fc267e48a58cd8CAS |
Humblot, P. (2001). Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants. Theriogenology 56, 1417–1433.
| Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XjslyqsA%3D%3D&md5=19e9eef9b618294833100cab24f65263CAS |
Jammes, H., Junien, C., and Chavatte-Palmer, P. (2011). Epigenetic control of development and expression of quantitative traits. Reprod. Fertil. Dev. 23, 64–74.
| Epigenetic control of development and expression of quantitative traits.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhvVyqsLY%3D&md5=a6fe7959151594bbfce2da5ab32e23faCAS |
Kim, S., Choi, Y., Spencer, T. E., and Bazer, F. W. (2003). Effects of the estrous cycle, pregnancy and interferon tau on expression of cyclooxygenase two (COX-2) in ovine endometrium. Reprod. Biol. Endocrinol. 1, 58.
| Effects of the estrous cycle, pregnancy and interferon tau on expression of cyclooxygenase two (COX-2) in ovine endometrium.Crossref | GoogleScholarGoogle Scholar |
Kimmins, S., and MacLaren, L. A. (2001). Oestrous cycle and pregnancy effects on the distribution of oestrogen and progesterone receptors in bovine endometrium. Placenta 22, 742–748.
| Oestrous cycle and pregnancy effects on the distribution of oestrogen and progesterone receptors in bovine endometrium.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXotFaqu7Y%3D&md5=e906d8990378cbcbbe50c97457f64ecbCAS |
Kindahl, H., Edqvist, L. E., Granstrom, E., and Bane, A. (1976). The release of prostaglandin F2alpha as reflected by 15-keto-13,14-dihydroprostaglandin F2alpha in the peripheral circulation during normal luteolysis in heifers. Prostaglandins 11, 871–878.
| The release of prostaglandin F2alpha as reflected by 15-keto-13,14-dihydroprostaglandin F2alpha in the peripheral circulation during normal luteolysis in heifers.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaE28Xks1Snsb0%3D&md5=20fce40aa7a30ec44b4655c5006394f3CAS |
Klein, C., Bauersachs, S., Ulbrich, S. E., Einspanier, R., Meyer, H. H., Schmidt, S. E., Reichenbach, H. D., Vermehren, M., Sinowatz, F., Blum, H., and Wolf, E. (2006). Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period. Biol. Reprod. 74, 253–264.
| Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xot1Kmuw%3D%3D&md5=d569ce74b516a2f52e0e3923e2bb99edCAS |
Lee, R. S., Peterson, A. J., Donnison, M. J., Ravelich, S., Ledgard, A. M., Li, N., Oliver, J. E., Miller, A. L., Tucker, F. C., Breier, B., and Wells, D. N. (2004). Cloned cattle fetuses with the same nuclear genetics are more variable than contemporary half-siblings resulting from artificial insemination and exhibit fetal and placental growth deregulation even in the first trimester. Biol. Reprod. 70, 1–11.
| Cloned cattle fetuses with the same nuclear genetics are more variable than contemporary half-siblings resulting from artificial insemination and exhibit fetal and placental growth deregulation even in the first trimester.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2cXhvVOm&md5=4888640cece0ad3b91a774565ca47ad4CAS |
Leroy, J. L. M. R., Van Hoeck, V., Clemente, M., Rizos, D., Gutierrez-Adan, A., Van Soom, A., Uytterhoeven, M., and Bols, P. E. J. (2010). The effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality. Hum. Reprod. 25, 768–778.
| The effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXitFeitr8%3D&md5=77e68d7f784aaa37fa565bd39f2922dfCAS |
Leroy, J. L. M. R., Rizos, D., Sturmey, R., Bossaert, P., Gutierrez-Adan, A., Van Hoeck, V., Valckx, S., and Bols, P. E. J. (2012). Intrafollicular conditions as a major link between maternal metabolism and oocyte quality: a focus on dairy cow fertility. Reprod. Fertil. Dev. 24, 1–12.
| Intrafollicular conditions as a major link between maternal metabolism and oocyte quality: a focus on dairy cow fertility.Crossref | GoogleScholarGoogle Scholar |
Lewis, G. S., Thatcher, W. W., Bazer, F. W., and Curl, J. S. (1982). Metabolism of arachidonic acid in vitro by bovine blastocysts and endometrium. Biol. Reprod. 27, 431–439.
| Metabolism of arachidonic acid in vitro by bovine blastocysts and endometrium.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaL38XlslGrtro%3D&md5=6a41ee1a7b0aa040cd6a17df5ec62309CAS |
Li, J., and Roberts, R. M. (1994). Interferon-tau and interferon-alpha interact with the same receptors in bovine endometrium. Use of a readily iodinatable form of recombinant interferon-tau for binding studies. J. Biol. Chem. 269, 13 544–13 550.
| 1:CAS:528:DyaK2cXjt1WitLw%3D&md5=d3bf19b9b5a28c91884c70972b04305eCAS |
Madore, E., Harvey, N., Parent, J., Chapdelaine, P., Arosh, J. A., and Fortier, M. A. (2003). An aldose reductase with 20 alpha-hydroxysteroid dehydrogenase activity is most likely the enzyme responsible for the production of prostaglandin f2 alpha in the bovine endometrium. J. Biol. Chem. 278, 11 205–11 212.
| An aldose reductase with 20 alpha-hydroxysteroid dehydrogenase activity is most likely the enzyme responsible for the production of prostaglandin f2 alpha in the bovine endometrium.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXit1KgsLk%3D&md5=dba228d159fe8026c07e7dd8162fce65CAS |
Mamo, S., Mehta, J. P., McGettigan, P., Fair, T., Spencer, T. E., Bazer, F. W., and Lonergan, P. (2011). RNA sequencing reveals novel gene clusters in bovine conceptuses associated with maternal recognition of pregnancy and implantation. Biol. Reprod. 85, 1143–1151.
| RNA sequencing reveals novel gene clusters in bovine conceptuses associated with maternal recognition of pregnancy and implantation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhs1ShsLbO&md5=cc381d3e4fd486add3b3b8b8993df828CAS |
Mamo, S., Mehta, J. P., Forde, N., McGettigan, P., and Lonergan, P. (2012). Conceptus–endometrium crosstalk during maternal recognition of pregnancy in cattle. Biol. Reprod. 87, 6.
| Conceptus–endometrium crosstalk during maternal recognition of pregnancy in cattle.Crossref | GoogleScholarGoogle Scholar |
Mann, G. E., Lamming, G. E., Robinson, R. S., and Wathes, D. C. (1999). The regulation of interferon-tau production and uterine hormone receptors during early pregnancy. J. Reprod. Fertil. Suppl. 54, 317–328.
| 1:CAS:528:DyaK1MXnslSitrc%3D&md5=d2c1c05806f84f83d0abf86bcf180f28CAS |
Mansouri-Attia, N., Aubert, J., Reinaud, P., Giraud-Delville, C., Taghouti, G., Galio, L., Everts, R. E., Degrelle, S., Richard, C., Hue, I., Yang, X., Tian, X. C., Lewin, H. A., Renard, J. P., and Sandra, O. (2009a). Gene expression profiles of bovine caruncular and intercaruncular endometrium at implantation. Physiol. Genomics 39, 14–27.
| Gene expression profiles of bovine caruncular and intercaruncular endometrium at implantation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXhtlakt7rM&md5=098db221572bb0da85c578e106f8034cCAS |
Mansouri-Attia, N., Sandra, O., Aubert, J., Degrelle, S., Everts, R. E., Giraud-Delville, C., Heyman, Y., Galio, L., Hue, I., Yang, X., Tian, X. C., Lewin, H. A., and Renard, J. P. (2009b). Endometrium as an early sensor of in vitro embryo manipulation technologies. Proc. Natl Acad. Sci. USA 106, 5687–5692.
| Endometrium as an early sensor of in vitro embryo manipulation technologies.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXkvFGhurY%3D&md5=0a3c92b5d12d25bd355270044977da8dCAS |
Marcus, G. J. (1981). Prostaglandin formation by the sheep embryo and endometrium as an indication of maternal recognition of pregnancy. Biol. Reprod. 25, 56–64.
| Prostaglandin formation by the sheep embryo and endometrium as an indication of maternal recognition of pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaL3MXltlSgtb0%3D&md5=27a67d9f51f57d784d380e26470db324CAS |
McCracken, J. A., Custer, E. E., and Lamsa, J. C. (1999). Luteolysis: a neuroendocrine-mediated event. Physiol. Rev. 79, 263–323.
| 1:CAS:528:DyaK1MXivFektLg%3D&md5=abfac6ad74dd0777ec3f613a1520e3c4CAS |
Meier, S., Ledgard, A. M., Sato, T. A., Peterson, A. J., and Mitchell, M. D. (2009). Polyunsaturated fatty acids differentially alter PGF(2alpha) and PGE(2) release from bovine trophoblast and endometrial tissues during short-term culture. Anim. Reprod. Sci. 111, 353–360.
| Polyunsaturated fatty acids differentially alter PGF(2alpha) and PGE(2) release from bovine trophoblast and endometrial tissues during short-term culture.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhsFKmt7Y%3D&md5=f75983a7c3d423f13526d0d640c9a6c2CAS |
Meyer, H. H. (1994). Luteal versus placental progesterone: the situation in the cow, pig and bitch. Exp. Clin. Endocrinol. 102, 190–192.
| Luteal versus placental progesterone: the situation in the cow, pig and bitch.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK2cXlsV2gtLo%3D&md5=cd0de3b96da29014ae60c253884b269cCAS |
Michael, D. D., Alvarez, I. M., Ocon, O. M., Powell, A. M., Talbot, N. C., Johnson, S. E., and Ealy, A. D. (2006). Fibroblast growth factor-2 is expressed by the bovine uterus and stimulates interferon-tau production in bovine trophectoderm. Endocrinology 147, 3571–3579.
| Fibroblast growth factor-2 is expressed by the bovine uterus and stimulates interferon-tau production in bovine trophectoderm.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XmtlOrsbk%3D&md5=a1c9b824f133af1c8ade487929c5bb89CAS |
Mitko, K., Ulbrich, S. E., Wenigerkind, H., Sinowatz, F., Blum, H., Wolf, E., and Bauersachs, S. (2008). Dynamic changes in messenger RNA profiles of bovine endometrium during the oestrous cycle. Reproduction 135, 225–240.
| Dynamic changes in messenger RNA profiles of bovine endometrium during the oestrous cycle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXit1yrtLo%3D&md5=e4e4bf37f2b0462f2cc25d7fccb0b404CAS |
Mullen, M. P., Elia, G., Hilliard, M., Parr, M. H., Diskin, M. G., Evans, A. C., and Crowe, M. A. (2012). Proteomic characterization of histotroph during the preimplantation phase of the estrous cycle in cattle. J. Proteome Res. 11, 3004–3018.
| Proteomic characterization of histotroph during the preimplantation phase of the estrous cycle in cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XkslWju7c%3D&md5=6bfce66c2f1a99097f8b8d15a6c702eaCAS |
Østrup, E., Hyttel, P., and Østrup, O. (2011). Embryo–maternal communication: signalling before and during placentation in cattle and pig. Reprod. Fertil. Dev. 23, 964–975.
| Embryo–maternal communication: signalling before and during placentation in cattle and pig.Crossref | GoogleScholarGoogle Scholar |
Parent, J., Chapdelaine, P., Sirois, J., and Fortier, M. A. (2002). Expression of microsomal prostaglandin E synthase in bovine endometrium: coexpression with cyclooxygenase type 2 and regulation by interferon-tau. Endocrinology 143, 2936–2943.
| Expression of microsomal prostaglandin E synthase in bovine endometrium: coexpression with cyclooxygenase type 2 and regulation by interferon-tau.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38Xls1Sgtrc%3D&md5=157d1304945ae533de86cb07b0cfce13CAS |
Parent, M., Madore, E., MacLaren, L. A., and Fortier, M. A. (2006). 15-Hydroxyprostaglandin dehydrogenase in the bovine endometrium during the oestrous cycle and early pregnancy. Reproduction 131, 573–582.
| 15-Hydroxyprostaglandin dehydrogenase in the bovine endometrium during the oestrous cycle and early pregnancy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xjs12jsLc%3D&md5=c79465392a50fad915d1460c0d92afdbCAS |
Reik, W. (2007). Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447, 425–432.
| Stability and flexibility of epigenetic gene regulation in mammalian development.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXlsFOgs7w%3D&md5=b96820de7e1761cf7bc003dd4af37d4dCAS |
Roberts, R. M., Ezashi, T., Rosenfeld, C. S., Ealy, A. D., and Kubisch, H. M. (2003). Evolution of the interferon tau genes and their promoters, and maternal-trophoblast interactions in control of their expression. Reprod. Suppl. 61, 239–251.
| 1:CAS:528:DC%2BD3sXptFKhsbs%3D&md5=641a1de8071295b613aff936f852682dCAS |
Robinson, R. S., Mann, G. E., Lamming, G. E., and Wathes, D. C. (1999). The effect of pregnancy on the expression of uterine oxytocin, oestrogen and progesterone receptors during early pregnancy in the cow. J. Endocrinol. 160, 21–33.
| The effect of pregnancy on the expression of uterine oxytocin, oestrogen and progesterone receptors during early pregnancy in the cow.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1MXjs12ktbg%3D&md5=dc7cca4d9e69d27fee485dd8e9df4598CAS |
Robinson, R. S., Mann, G. E., Lamming, G. E., and Wathes, D. C. (2001). Expression of oxytocin, oestrogen and progesterone receptors in uterine biopsy samples throughout the oestrous cycle and early pregnancy in cows. Reproduction 122, 965–979.
| Expression of oxytocin, oestrogen and progesterone receptors in uterine biopsy samples throughout the oestrous cycle and early pregnancy in cows.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XhvVWitQ%3D%3D&md5=28f81d2b907cb825ae4c48a6be697d9bCAS |
Robinson, R. S., Fray, M. D., Wathes, D. C., Lamming, G. E., and Mann, G. E. (2006). In vivo expression of interferon tau mRNA by the embryonic trophoblast and uterine concentrations of interferon tau protein during early pregnancy in the cow. Mol. Reprod. Dev. 73, 470–474.
| In vivo expression of interferon tau mRNA by the embryonic trophoblast and uterine concentrations of interferon tau protein during early pregnancy in the cow.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XisFals74%3D&md5=0947f9e36f7ca8cbcd0d765b77183880CAS |
Robinson, R. S., Hammond, A. J., Wathes, D. C., Hunter, M. G., and Mann, G. E. (2008). Corpus luteum–endometrium–embryo interactions in the dairy cow: underlying mechanisms and clinical relevance. Reprod. Domest. Anim. 43, 104–112.
| Corpus luteum–endometrium–embryo interactions in the dairy cow: underlying mechanisms and clinical relevance.Crossref | GoogleScholarGoogle Scholar |
Rosenfeld, C. S., Han, C. S., Alexenko, A. P., Spencer, T. E., and Roberts, R. M. (2002). Expression of interferon receptor subunits, IFNAR1 and IFNAR2, in the ovine uterus. Biol. Reprod. 67, 847–853.
| Expression of interferon receptor subunits, IFNAR1 and IFNAR2, in the ovine uterus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XmsV2jsLY%3D&md5=86cdff483ab9f81ffac70e10c051717dCAS |
Rottmayer, R., Ulbrich, S. E., Kolle, S., Prelle, K., Neumueller, C., Sinowatz, F., Meyer, H. H., Wolf, E., and Hiendleder, S. (2006). A bovine oviduct epithelial cell suspension culture system suitable for studying embryo–maternal interactions: morphological and functional characterization. Reproduction 132, 637–648.
| A bovine oviduct epithelial cell suspension culture system suitable for studying embryo–maternal interactions: morphological and functional characterization.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xht1ahs7rJ&md5=9ed279c8622a3aa98629493001b72b62CAS |
Santos, F., Zakhartchenko, V., Stojkovic, M., Peters, A., Jenuwein, T., Wolf, E., Reik, W., and Dean, W. (2003). Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr. Biol. 13, 1116–1121.
| Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXlt1entrY%3D&md5=7fbd3ad7e2d64efdb1e2190605e6c716CAS |
Schams, D. (1987). Luteal peptides and intercellular communication. J. Reprod. Fertil. Suppl. 34, 87–99.
| 1:CAS:528:DyaL2sXltV2nsrw%3D&md5=27cc9ac0be7215647efd544250c4426cCAS |
Seki, Y., Williams, L., Vuguin, P. M., and Charron, M. J. (2012). Minireview: epigenetic programming of diabetes and obesity: animal models. Endocrinology 153, 1031–1038.
| Minireview: epigenetic programming of diabetes and obesity: animal models.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38Xjs1antrk%3D&md5=6055d6bae000f747000f79b1582d2bd7CAS |
Shelton, K., Parkinson, T. J., Hunter, M. G., Kelly, R. W., and Lamming, G. E. (1990). Prostaglandin E-2 as a potential luteotrophic agent during early pregnancy in cattle. J. Reprod. Fertil. 90, 11–17.
| Prostaglandin E-2 as a potential luteotrophic agent during early pregnancy in cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK3MXjs1Ghsw%3D%3D&md5=a3e3b1988e866c4c24f0aa8bcf900106CAS |
Silva, L. A., and Ginther, O. J. (2010). Local effect of the conceptus on uterine vascular perfusion during early pregnancy in heifers. Reproduction 139, 453–463.
| Local effect of the conceptus on uterine vascular perfusion during early pregnancy in heifers.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXitFKitLc%3D&md5=ec3ece295c1a1232f030a3f7e30cfeb6CAS |
Sinclair, K. D., Karamitri, A., and Gardner, D. S. (2010). Dietary regulation of developmental programming in ruminants: epigenetic modifications in the germline. Soc. Reprod. Fertil. Suppl. 67, 59–72.
| 1:STN:280:DC%2BC3MnosFegsQ%3D%3D&md5=41a1117df32189cdec3d329588d3e9eaCAS |
Spencer, T. E., and Bazer, F. W. (1995). Temporal and spatial alterations in uterine estrogen receptor and progesterone receptor gene expression during the estrous cycle and early pregnancy in the ewe. Biol. Reprod. 53, 1527–1543.
| Temporal and spatial alterations in uterine estrogen receptor and progesterone receptor gene expression during the estrous cycle and early pregnancy in the ewe.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK2MXpsVeisL8%3D&md5=816e9cf0354535ad37efc48e74756c4fCAS |
Spencer, T. E., Mirando, M. A., Mayes, J. S., Watson, G. H., Ott, T. L., and Bazer, F. W. (1996). Effects of interferon-tau and progesterone on oestrogen-stimulated expression of receptors for oestrogen, progesterone and oxytocin in the endometrium of ovariectomized ewes. Reprod. Fertil. Dev. 8, 843–853.
| Effects of interferon-tau and progesterone on oestrogen-stimulated expression of receptors for oestrogen, progesterone and oxytocin in the endometrium of ovariectomized ewes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK28XlvVKlurs%3D&md5=9fabf372a189201dde1fe4732d6df1f8CAS |
Spencer, T. E., Sandra, O., and Wolf, E. (2008). Genes involved in conceptus–endometrial interactions in ruminants: insights from reductionism and thoughts on holistic approaches. Reproduction 135, 165–179.
| Genes involved in conceptus–endometrial interactions in ruminants: insights from reductionism and thoughts on holistic approaches.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXit1yrtL4%3D&md5=70f57bdd36a14c692f0988d9f759c822CAS |
Stormshak, F., and Bishop, C. V. (2008). Board-invited review: estrogen and progesterone signaling: genomic and nongenomic actions in domestic ruminants. J. Anim. Sci. 86, 299–315.
| Board-invited review: estrogen and progesterone signaling: genomic and nongenomic actions in domestic ruminants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhsVajsrc%3D&md5=255ed3212da56a7e477d289c12a9f78eCAS |
Telgmann, R., Bathgate, R. A., Jaeger, S., Tillmann, G., and Ivell, R. (2003). Transcriptional regulation of the bovine oxytocin receptor gene. Biol. Reprod. 68, 1015–1026.
| Transcriptional regulation of the bovine oxytocin receptor gene.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXhsFGksL4%3D&md5=eb52323670691a7d44209ce3f43950b4CAS |
Thatcher, W. W., Guzeloglu, A., Mattos, R., Binelli, M., Hansen, T. R., and Pru, J. K. (2001). Uterine-conceptus interactions and reproductive failure in cattle. Theriogenology 56, 1435–1450.
| Uterine-conceptus interactions and reproductive failure in cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XjslyqsQ%3D%3D&md5=e5f50c8f5f7e33978abe860465ab0878CAS |
Tithof, P. K., Roberts, M. P., Guan, W., Elgayyar, M., and Godkin, J. D. (2007). Distinct phospholipase A2 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial cells. Reprod. Biol. Endocrinol. 5, 16.
| Distinct phospholipase A2 enzymes regulate prostaglandin E2 and F2alpha production by bovine endometrial epithelial cells.Crossref | GoogleScholarGoogle Scholar |
Ulbrich, S. E., Schulke, K., Groebner, A. E., Reichenbach, H. D., Angioni, C., Geisslinger, G., and Meyer, H. H. (2009). Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. Reproduction 138, 371–382.
| Quantitative characterization of prostaglandins in the uterus of early pregnant cattle.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXptlemtLg%3D&md5=95fc20f2e8fc977c4492272ccc2d997dCAS |
Ulbrich, S. E., Zitta, K., Hiendleder, S., and Wolf, E. (2010). In vitro systems for intercepting early embryo–maternal cross-talk in the bovine oviduct. Theriogenology 73, 802–816.
| In vitro systems for intercepting early embryo–maternal cross-talk in the bovine oviduct.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXivFGltr0%3D&md5=0c9097ba61542d9d898825d7838c6624CAS |
Van Soom, A., Vandaele, L., Peelman, L. J., Goossens, K., and Fazeli, A. (2010). Modeling the interaction of gametes and embryos with the maternal genital tract: from in vivo to in silico. Theriogenology 73, 828–837.
| Modeling the interaction of gametes and embryos with the maternal genital tract: from in vivo to in silico.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3c7otlCmtA%3D%3D&md5=49e52bc25490b6b8880c421ada059352CAS |
Walker, C. G., Meier, S., Littlejohn, M. D., Lehnert, K., Roche, J. R., and Mitchell, M. D. (2010). Modulation of the maternal immune system by the pre-implantation embryo. BMC Genomics 11, 474.
| Modulation of the maternal immune system by the pre-implantation embryo.Crossref | GoogleScholarGoogle Scholar |
Wang, B., Xiao, C., and Goff, A. K. (2003). Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium. Biol. Reprod. 68, 673–679.
| Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXntVCgtg%3D%3D&md5=eb48aa4b3d008d78d8705b9bcfe3f188CAS |
Waters, S. M., Coyne, G. S., Kenny, D. A., Machugh, D. E., and Morris, D. G. (2012). Dietary n-3 polyunsaturated fatty acid supplementation alters the expression of genes involved in the control of fertility in the bovine uterine endometrium. Physiol. Genomics , .
| Dietary n-3 polyunsaturated fatty acid supplementation alters the expression of genes involved in the control of fertility in the bovine uterine endometrium.Crossref | GoogleScholarGoogle Scholar |
Wathes, D. C., and Lamming, G. E. (1995). The oxytocin receptor, luteolysis and the maintenance of pregnancy. J. Reprod. Fertil. Suppl. 49, 53–67.
| 1:CAS:528:DyaK2MXmslWit7k%3D&md5=efe32ce2ffdd193bf420825217e3c194CAS |
