Embryo–maternal communication: signalling before and during placentation in cattle and pig
Esben Østrup A B D , Poul Hyttel C and Olga Østrup B CA Section of Biomaterials, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, Norway.
B Norwegian Center for Stem Cell Research, University of Oslo, 0317 Oslo, Norway.
C Section for Anatomy and Cell Biology, Department of Basic Animal and Veterinary Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark.
D Corresponding author. Email: esostrup@gmail.com
Reproduction, Fertility and Development 23(8) 964-975 https://doi.org/10.1071/RD11140
Submitted: 27 March 2011 Accepted: 30 August 2011 Published: 27 September 2011
Abstract
Communication during early pregnancy is essential for successful reproduction. In this review we address the beginning of the communication between mother and developing embryo; including morphological and transcriptional changes in the endometrium as well as epigenetic regulation mechanisms directing the placentation. An increasing knowledge of the embryo–maternal communication might not only help to improve the fertility of our farm animals but also our understanding of human health and reproduction.
Additional keywords: bovine, implantation, imprinting, interferon, interleukin, methylation, oestrogen, porcine.
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