
%0 Journal Article
%A Lobley, RW 
%A Burrows, PC 
%A Pemberton, PW 
%A Bradbury, FM 
%A D'Souza, SW 
%A Smart, JL 
%T Longitudinal variation in the activities of mucosal enzymes in the small intestine of suckling rats
%J Reproduction, Fertility and Development
%D 1996/05/01
%V 8
%N 3
%P 439-441
%K 
%R https://doi.org/10.1071/RD9960439
%U https://www.publish.csiro.au/paper/RD9960439 
%X The extent of positional variation in mucosal enzyme activity along the small intestine was investigated in 14-day-old suckling rats. Samples were taken from ten equally spaced sites along the intestine in 11 rat pups and the activities of the enzymes alkaline phosphatase, neutral aminopeptidase, gamma-glutamyl transferase, lactase and sucrase were measured. All the enzymes except sucrase were subject to considerable positional variation. Alkaline phosphatase and aminopeptidase activities were distributed throughout the intestine, with a broad maximum in the distal intestine. Lactase was also broadly distributed but with greatest activity in the mid intestine. gamma-glutamyl transferase exhibited a novel profile, with a very high proportion of the total activity (78%) present in the distal intestine. Sucrase was essentially absent throughout the intestine. 
