
%0 Journal Article
%A Jaggi, M 
%A Mehrotra, PK 
%A Maitra, SC 
%A Agarwal, SL 
%A Das, K 
%A Kamboj, VP 
%T Ultrastructure of cellular components of human trophoblasts during early pregnancy
%J Reproduction, Fertility and Development
%D 1995/12/01
%V 7
%N 6
%P 1539-1546
%K 
%R https://doi.org/10.1071/RD9951539
%U https://www.publish.csiro.au/paper/RD9951539 
%X Two cell types, the cyto- and syncytio-trophoblasts, were identified in human chorionic villi of 6-10 weeks' gestation. The intracellular organization of these cells was examined. Ultrathin sections of small pieces of chorionic villi revealed the presence of a multinucleate syncytiotrophoblastic layer, whose surface was covered with microvilli. The cytotrophoblasts, however, had a single large nucleus with a prominent nucleolus. An interesting feature of the basement membrane of these cells was the presence of aggregates of dark granules in samples of the earlier gestational age (6-8 weeks) and granular bodies having a dense outer ring and a translucent inner ring with a lucid central area in samples of 8-10 weeks' gestation. Both types of granules are mineralized and are assumed to perform a buffering role for maintaining the neutrality of the layer. 
