
TY  - JOUR
A1  - Flint, AP 
T1  - Interferon, the oxytocin receptor and the maternal recognition of pregnancy in ruminants and non-ruminants: a comparative approach
JF  - Reproduction, Fertility and Development
JO  - Reprod. Fertil. Dev.
Y1  - 1995
VL  - 7
IS  - 3
SP  - 313
EP  - 318
KW  - 
UR  - https://doi.org/10.1071/RD9950313 
N2  - Ruminant and non-ruminant members of the Artiodactyla appear to use different mechanisms for the maternal recognition of pregnancy. In ruminants, the trophoblast of the developing blastocyst produces a characteristic Type I interferon of the interferon-tau family; this acts by blocking endometrial synthesis of the oxytocin receptor. A similar mechanism applies to domestic ruminants (sheep, cow, goat) and deer. In roe deer, which have embryonic diapause and are monoestrus, there is no requirement for a pre-implantation blastocyst signal to ensure maternal recognition of pregnancy. This paper compares the mechanisms leading to the maternal recognition of pregnancy in ruminants with that suggested to occur in a non-ruminant (the domestic pig). 
ER  -

