
%0 Journal Article
%A Gonzales, GF 
%A Risbridger, GP 
%A Hodgson, YH 
%A Pollanen, P 
%A de, Kretser DM 
%T Stage-specific inhibin secretion by rat seminiferous tubules
%J Reproduction, Fertility and Development
%D 1989/09/01
%V 1
%N 3
%P 275-279
%K 
%R https://doi.org/10.1071/RD9890275
%U https://www.publish.csiro.au/paper/RD9890275 
%X The endogenous inhibin content was measured by radioimmunoassay in segments of seminiferous tubules at specific stages of the spermatogenic cycle isolated by transillumination-assisted dissection as described by Parvinen (1982). In addition, the immunoactive inhibin production in response to FSH stimulation was investigated. The inhibin content was greatest in tubules at stages II-VI of the cycle and was lowest at stages VII-VIII. Over 48 h of culture, the secretion of inhibin into the medium was greatest at stages XIII-VI and lowest at stages VII-VIII. The inhibin response to FSH stimulation was greatest at stages IX-XIII and least at stages VII-VIII. The results demonstrate that the secretion of inhibin by adult tubules in vitro varies according to the stage of the seminiferous cycle. 
