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The DNA methylation profile of oocytes in mice with hyperinsulinaemia and hyperandrogenism as detected by single-cell level whole genome bisulphite sequencing (SC-WGBS) technology

Qian-Nan Li A B , Lei Guo C , Yi Hou B , Xiang-Hong Ou C , Zhonghua Liu A and Qing-Yuan Sun A B D E
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A College of Life Science, Northeast Agricultural University, #600 Changjiang Road, Harbin 150030, China.

B State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, #1 Beichen West Road, Beijing 100101, China.

C Fertility Preservation Lab, Reproductive Medicine Centre, Guangdong Second Provincial General Hospital, The Second Peoples’ Hospital of Guangdong Province, #466 Xingang Road, Guangzhou 510317, China.

D Qingdao Agricultural University, #700 Changcheng Road, Qingdao 266109, China.

E Corresponding author. Email: sunqy@ioz.ac.cn

Reproduction, Fertility and Development 30(12) 1713-1719 https://doi.org/10.1071/RD18002
Submitted: 2 January 2018  Accepted: 16 May 2018   Published: 22 June 2018



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