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Obesity is associated with altered metabolic and reproductive activity in the mare: effects of metformin on insulin sensitivity and reproductive cyclicity*

M. M. Vick A , D. R. Sessions A , B. A. Murphy A , E. L. Kennedy A , S. E. Reedy A and B. P. Fitzgerald A B
+ Author Affiliations
- Author Affiliations

A Department of Veterinary Science, Maxwell Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA.

B Corresponding author. Email: bfitz@uky.edu

Reproduction, Fertility and Development 18(6) 609-617 https://doi.org/10.1071/RD06016
Submitted: 28 February 2006  Accepted: 9 April 2006   Published: 9 June 2006



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Pharmacokinetics and bioavailability of metformin in horses
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American Journal of Veterinary Research. 2009 70(5). p.665
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