Consideration of gender in diagnosis and management of blood-borne viruses: the case of hepatitis C
Anna Olsen A D , Meredith Temple-Smith B and Cathy Banwell C
+ Author Affiliations
- Author Affiliations
A The Kirby Institute, The University of New South Wales, Sydney, NSW 2052, Australia.
B Department of General Practice, The University of Melbourne, 200 Berkeley Street, Parkville, Melbourne, Vic. 3054, Australia.
C National Centre for Epidemiology and Population Health, The Australian National University, Canberra, ACT 0200, Australia.
D Corresponding author. Email: aolsen@kirby.unsw.edu.au
Australian Journal of Primary Health 19(2) 124-129 https://doi.org/10.1071/PY11127
Submitted: 3 October 2011 Accepted: 6 May 2012 Published: 31 May 2012
Abstract
Gender-sensitive health education and clinical management are key components of successful care for people living with chronic illness, yet there is little research available on the specific needs of women living with hepatitis C viral (HCV) infection. This paper reports on a qualitative investigation of HCV diagnosis, symptoms, health care and wellbeing among 109 women living with HCV in two major cities in Australia. Women’s experiences of HCV reflect several gender-specific needs around diagnosis, reproductive health and psycho-social wellbeing. Personal relationships were central to women’s experiences of health and health care and remained dominant in their considerations for the future. Particularly because women are more likely than men to be responsible for family, we highlight the need to consider the social issues of stigma, poverty and drug use when caring for Australian women living with HCV.
Additional keywords: drug use, patient perspective, reproductive health, women.
References
Abs R, Verhelst J, Maeyaert J, Van Buyten JP, Opsomer F, Adriaensen H, Verlooy J, Van Havenbergh T, Smet M, Van Acker K (2000) Endocrine consequences of long-term intrathecal administration of opioids. The Journal of Clinical Endocrinology and Metabolism 85, 2215–2222.| Endocrine consequences of long-term intrathecal administration of opioids.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3cXlsVequ7Y%3D&md5=c0869d8c120cfa174ee434db817bbb63CAS |
Bakr I, Rekacewicz C, El Hosseiny M, Ismail S, El Daly M, El-Kafrawy S, Esmat G, Hamid MA, Mohamed MK, Fontanet A (2006) Higher clearance of hepatitis C virus infection in females compared with males. Gut 55, 1183–1187.
| Higher clearance of hepatitis C virus infection in females compared with males.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD28vis1yqsg%3D%3D&md5=8b5cd311dd3cd3ca20ef186d12acad85CAS |
Banwell C, Bammer G, Gifford S, O’Brien M (2005) Australian lesbian and bisexual women’s health and social experiences of living with hepatitis C. Health Care for Women International 26, 340–354.
| Australian lesbian and bisexual women’s health and social experiences of living with hepatitis C.Crossref | GoogleScholarGoogle Scholar |
Banwell C, Dance P, Olsen A, Dixon J (2009) It fucks your insides up: the potential effects of opioid use on women’s sexual and reproductive functioning. Women’s Health & Urban Life 8, 14–27.
Charles N, Walters V (2008) ‘Men are leavers alone and women are worriers’: gender differences in discourses of health. Health Risk & Society 10, 117–132.
| ‘Men are leavers alone and women are worriers’: gender differences in discourses of health.Crossref | GoogleScholarGoogle Scholar |
Clinical Practice Improvement Unit (2005) ‘Literature review for three centres antenatal care consensus guidelines.’ (The Royal Women’s Hospital: Melbourne)
Commonwealth of Australia (2010) Third national hepatitis C strategy 2010–2013. Available at http://www.health.gov.au/internet/main/publishing.nsf/Content/ohp-national-strategies-2010-hcv/$File/hcv.pdf [Verified 25 May 2012]
Crockett B, Gifford SM (2004) ‘Eyes Wide Shut’: narratives of women living with hepatitis C in Australia. Women & Health 39, 117–137.
| ‘Eyes Wide Shut’: narratives of women living with hepatitis C in Australia.Crossref | GoogleScholarGoogle Scholar |
Daniell HW (2008) Opioid endocrinopathy in women consuming prescribed sustained-action opioids for control of nonmalignant pain. The Journal of Pain 9, 28–36.
| Opioid endocrinopathy in women consuming prescribed sustained-action opioids for control of nonmalignant pain.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhtlWltg%3D%3D&md5=01196119c71f91b2e800e7f6b4d2e9d8CAS |
Di Martino V, Lebray P, Myers RP, Pannier E, Paradis V, Charlotte F, Moussalli J, Thabut D, Buffet C, Poynard T (2004) Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure. Hepatology 40, 1426–1433.
| Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXhslagtQ%3D%3D&md5=0cc1fe943c2aab424b094ca85a963ce1CAS |
Doab A, Treloar C, Dore G (2005) Hepatitis C treatment knowledge, attitudes and barriers among current injecting drug users in Australia. Clinical Infectious Diseases 40, S313–S320.
| Hepatitis C treatment knowledge, attitudes and barriers among current injecting drug users in Australia.Crossref | GoogleScholarGoogle Scholar |
Doyal L (2001) Sex, gender, and health: the need for a new approach. British Medical Journal 323, 1061–1063.
| Sex, gender, and health: the need for a new approach.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3MnktVCgtw%3D%3D&md5=be883bb528b1c0e71bce564e5fa70126CAS |
Dunne EA, Quayle E (2001) The impact of iatrogenically acquired hepatitis C infection on the well-being and relationships of a group of Irish women. Journal of Health Psychology 6, 679–692.
| The impact of iatrogenically acquired hepatitis C infection on the well-being and relationships of a group of Irish women.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3MbmtFeksw%3D%3D&md5=822cfe57673ef840ffe0d88f2b024018CAS |
Gifford SM, O’Brien ML, Bammer G, Banwell C, Stoové M (2003) Australian women’s experiences of living with hepatitis C virus: results from a cross-sectional survey. Journal of Gastroenterology and Hepatology 18, 841–850.
| Australian women’s experiences of living with hepatitis C virus: results from a cross-sectional survey.Crossref | GoogleScholarGoogle Scholar |
Gifford SM, O’Brien ML, Smith A, Temple-Smith M, Drew M, Jolley D (2005) Australian men’s experiences of living with hepatitis C virus: results from a cross-sectional survey. Journal of Gastroenterology and Hepatology 20, 79–86.
| Australian men’s experiences of living with hepatitis C virus: results from a cross-sectional survey.Crossref | GoogleScholarGoogle Scholar |
Giles M, Hellard M, Sasadeusz J (2003) Hepatitis C and pregnancy: an update. Australian and New Zealand Journal of Obstetrics and Gynaecology 43, 290–293.
| Hepatitis C and pregnancy: an update.Crossref | GoogleScholarGoogle Scholar |
Hayashi J, Kishihara Y, Ueno K, Yamaji K, Kawakami Y, Furusyo N, Sawayama Y, Kashiwagi S (1998) Age-related response to interferon alfa treatment in women vs men with chronic hepatitis C virus infection. Archives of Internal Medicine 158, 177–181.
| Age-related response to interferon alfa treatment in women vs men with chronic hepatitis C virus infection.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1cXoslCksw%3D%3D&md5=d0b40306bdd4eea44e613c4d71dd9016CAS |
Iversen J, Wand H, Gonnermann A, Maher L (2010) Gender differences in hepatitis C antibody prevalence and risk behaviours among people who inject drugs in Australia 1998−2008. The International Journal on Drug Policy 21, 471–476.
| Gender differences in hepatitis C antibody prevalence and risk behaviours among people who inject drugs in Australia 1998−2008.Crossref | GoogleScholarGoogle Scholar |
Kelly MP, Field D (1996) Medical sociology, chronic illness and the body. Sociology of Health & Illness 18, 241–257.
| Medical sociology, chronic illness and the body.Crossref | GoogleScholarGoogle Scholar |
Lenton E, Fraser S, Moore D, Treloar C (2011) Hepatitis C, love and intimacy: beyond the ‘anomalous body’. Drugs Education Prevention & Policy 18, 228–236.
| Hepatitis C, love and intimacy: beyond the ‘anomalous body’.Crossref | GoogleScholarGoogle Scholar |
McNally S, Temple-Smith M, Pitts M (2004) Making decisions about hepatitis C treatment: report to the Australian Government. The Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne.
Ministerial Advisory Committee on AIDS Sexual Health and Hepatitis Hepatitis C Sub-Committee (2006) ‘Hepatitis C virus projections working group: estimates and projections of the hepatitis C virus epidemic in Australia.’ (National Centre in HIV Epidemiology and Clinical Research, University of New South Wales: Sydney)
Muhr T, Friese S (2004) ‘User’s manual for ATLAS.ti 5.0.’ (Scientific Software Development: Berlin)
National Centre in HIV Epidemiology and Clinical Research (2010) HIV, viral hepatitis and sexually transmissible infections in Australia Annual Surveillance Report. The University of New South Wales, Sydney.
Pagliaro L, Peri V, Linea C, Camma C, Giunta M, Magrin S (1999) Natural history of chronic hepatitis C. Italian Journal of Gastroenterology and Hepatology 31, 28–44.
Popay J, Williams G, Thomas C, Gatrell A (1998) Theorising inequalities in health: the place of lay knowledge. Sociology of Health & Illness 20, 619–644.
| Theorising inequalities in health: the place of lay knowledge.Crossref | GoogleScholarGoogle Scholar |
Rhodes T (2002) The ‘risk environment’: a framework for understanding and reducing drug-related harm. The International Journal on Drug Policy 13, 85–94.
| The ‘risk environment’: a framework for understanding and reducing drug-related harm.Crossref | GoogleScholarGoogle Scholar |
Royal Women’s Hospital (2001) ‘Antenatal screening for hepatitis C virus (HCV).’ Available at http://3centres.com.au/guidelines/antenatal-screening-for-hepatitis-c-virus-hcv/ [Verified 16 February 2012]
Saltonstall R (1993) Health bodies, social bodies: men’s and women’s concepts and practices of health in everyday life. Social Science & Medicine 36, 7–14.
| Health bodies, social bodies: men’s and women’s concepts and practices of health in everyday life.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK3s7kt1Skuw%3D%3D&md5=de3fac5abe256bd7107cd86dd896bd34CAS |
Sartori M, Andorno S, Rigamonti C, Grossini E, Nicosia G, Boldorini R (2000) Chronic hepatitis C is mild in menstruating women. Journal of Gastroenterology and Hepatology 15, 1411–1417.
| Chronic hepatitis C is mild in menstruating women.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3M7jvFChtg%3D%3D&md5=b694f4fdbf7b67406148bef249b95e1dCAS |
Temple-Smith M, Gifford S, Stoové M (2004) The lived experience of men and women with hepatits C: implications for support and health information. Australian Health Review 27, 46–56.
| The lived experience of men and women with hepatits C: implications for support and health information.Crossref | GoogleScholarGoogle Scholar |
Temple-Smith M, Stoové M, Smith A, O’Brien M, Mitchell D, Banwell C, Bammer G, Jolley D, Gifford S (2007) Gender differences in seeking care for hepatitis C: the Australian experience. Journal of Substance Use 12, 59–70.
| Gender differences in seeking care for hepatitis C: the Australian experience.Crossref | GoogleScholarGoogle Scholar |
The Australian Injecting and Illicit Drug Users League (2004) The young women injecting drug users’ project final report. AIVL, Canberra.
Treloar C, Holt M (2008) Drug treatment clients’ readiness for hepatitis C treatment: implications for expanding treatment services in drug and alcohol settings. Australian Health Review 32, 570–576.
| Drug treatment clients’ readiness for hepatitis C treatment: implications for expanding treatment services in drug and alcohol settings.Crossref | GoogleScholarGoogle Scholar |
Villa E, Karampatou A, Cammà C, Di Leo A, Luongo M, Ferrari A, Petta S, Losi L, Taliani G, Trande P, Lei B, Graziosi A, Bernabucci V, Critelli R, Pazienza P, Rendina M, Antonelli A, Francavilla A (2011) Early menopause is associated with lack of response to antiviral therapy in women with chronic hepatitis C. Gastroenterology 140, 818–829.e2.
| Early menopause is associated with lack of response to antiviral therapy in women with chronic hepatitis C.Crossref | GoogleScholarGoogle Scholar |
Viral Hepatitis Prevention Board (2002) ‘Public health challenges for controlling HCV infection WHO informal consultation with VHPB.’ (WHO: Geneva)
Williams SJ (2005) ‘Medicine and the body.’ (Sage Publications)
Yamakawa Y, Sata M, Suzuki H, Noguchi S, Tanikawa K (1996) Higher elimination rate of hepatitis C virus among women. Journal of Viral Hepatitis 3, 317–321.
| Higher elimination rate of hepatitis C virus among women.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK2s7gtlGisA%3D%3D&md5=73e12acff58a6e685ba8ec5d25b577e9CAS |
