
%0 Journal Article
%A Ostrowski, Martin 
%A Tetu, Sasha 
%A Hassan, Karl 
%A Penesyan, Anahit 
%A Lim, Kent 
%A Elbourne, Liam 
%A Li, Liping 
%A Varkey, Deepa 
%A Paulsen, Ian 
%T From omics to systems biology: Exploring the mystery box of microbial life
%J Microbiology Australia
%D 2011/11/01
%V 32
%N 4
%P 147-150
%K 
%R https://doi.org/10.1071/MA11147
%U https://www.publish.csiro.au/paper/MA11147 
%X Microbial molecular biology has traditionally used very reductionist approaches; for example, find a gene of interest, clone it or knock it out and see if you can detect a phenotype. The genomics era has opened up the possibility of analysing microbes and communities at a systems level by combining high-throughput experimental data from genomic, transcriptomic, proteomic and phenomic techniques. This parallels earlier reductionist approaches by going from DNA to RNA to protein to phenotype, albeit on a global rather than individual gene scale. 
