
TY  - JOUR
A1  - Browning, GF 
A1  - Kanci, A 
A1  - Markham, PF 
T1  - Developing attenuated vaccines to control mycoplasmoses
JF  - Microbiology Australia
JO  - Microbiol. Aust.
Y1  - 2011
VL  - 32
IS  - 3
SP  - 121
EP  - 122
KW  - 
UR  - https://doi.org/10.1071/MA11121 
N2  - Temperature-sensitive strains of Mycoplasma gallisepticum, M. synoviae and M. hyopneumoniae, created using chemical mutagenesis, have proven to be effective vaccines against the three major mycoplasmoses causing disease in poultry and pigs. The use of these vaccines in poultry has significantly reduced reliance on antimicrobial therapy, with a consequent reduction in usage of macrolides. Recent advances in development of methods for genetic manipulation of mycoplasmas has enhanced our capacity to identify virulence genes, offering the prospect of the development of novel, rationally attenuated vaccines in the future. 
ER  -

