
%0 Journal Article
%A Kahler, Charlene 
%T Transcriptional repressors
%J Microbiology Australia
%D 2006/09/01
%V 27
%N 3
%P 105-108
%K 
%R https://doi.org/10.1071/MA06105
%U https://www.publish.csiro.au/paper/MA06105 
%X Prokaryotes regulate cellular functions in response to environmental cues via signal transduction pathways. In principal, there are two thematic organisations of signal transduction proteins: ? One-component proteins, in which the input and output domains are physically linked. These are commonly called activators (see article by Schubert &amp; Shearwin) and repressors (reviewed in this article). ? Two-component systems consisting of histidine kinases and response regulators (see article by Cheung &amp; Rood). A recent survey of 145 prokaryotic genomes has revealed the predominance of one-component systems in this domain of life and has provided the first indication of the diversity inherent in these signal transduction pathways. 
