
TY  - JOUR
A1  - D Nuttall, Stewart 
A1  - M Juraja, Suzy 
A1  - A Carmichael, Jennifer 
T1  - Beyond antibodies ? lessons from bacterial ?immunity?
JF  - Microbiology Australia
JO  - Microbiol. Aust.
Y1  - 2006
VL  - 27
IS  - 2
SP  - 80
EP  - 81
KW  - 
UR  - https://doi.org/10.1071/MA06080 
N2  - Isolation and production of highly specific protein-based binding molecules are crucial to the ever expanding diagnostics, therapeutics and protein array fields. Traditionally, such reagents have been sourced from vertebrate immune systems, where antibodies have evolved over millennia into highly effective molecules of immune surveillance capable of targeting a huge range of targets in response to infection and disease. Now, a growing number of alternative protein scaffolds are being investigated as specific binding molecules incorporating a diverse and powerful range of binding and recognition interfaces. These are being sourced from human proteins, from alternative immune molecules present in evolutionarily old vertebrates, and from highly evolved binding proteins in prokaryotic systems. 
ER  -

