
TY  - JOUR
A1  - Hunter, Neil 
A1  - Yap, Benjamin 
A1  - A Collyer, Charles 
A1  - J Crossley, Maxwell 
T1  - Targeting of a key pathogen in a polymicrobial infection
JF  - Microbiology Australia
JO  - Microbiol. Aust.
Y1  - 2005
VL  - 26
IS  - 3
SP  - 122
EP  - 123
KW  - 
UR  - https://doi.org/10.1071/MA05122 
N2  - The major oral diseases of caries and periodontitis are polymicrobial infections initiated by complex microbial biofilms that develop adjacent to the affected tissues. Bacterial plaque adherent to the tooth surface extends below the gingival margin and is increasingly dominated by facultative and obligate anaerobes. The dense plaque adherent to the tooth surface is in apparent equilibrium with a less structured fluid matrix that is in turn in some form of equilibrium with the biofilm adjacent to the surface of the epithelium that lines the gingival sulcus. The organisms that predominate in the epithelial biofilm are of particular interest with respect to the inflammatory disease of chronic periodontitis. 
ER  -

