
%0 Journal Article
%A Pittard, A. J. 
%A Cox, G. B. 
%T Frank William Ernest Gibson 1923&#8211;2008
%J Historical Records of Australian Science
%D 2010/05/06
%V 21
%N 1
%P 55-74
%K 
%R https://doi.org/10.1071/HR09024
%U https://www.publish.csiro.au/paper/HR09024 
%X Frank Gibson died in Canberra on 11 July 2008. Frank was a highly distinguished research scientist who will be remembered for his pioneering studies in identifying the branch-point compound in the pathway of biosynthesis of a large number of important aromatic compounds followed by a detailed biochemical and genetic analysis of many of the pathways leading to the aromatic amino acids and the so-called aromatic vitamins. Studies on ubiquinone synthesis and function led to an examination of oxidative phosphorylation and the structure and function of the F1F0-ATPase in the bacterium Escherichia coli. This work resulted in the formulation of a highly innovative model, involving rotating subunits of the F0 segment within the membrane and offering an explanation for the mechanism linking proton flow and ATP synthesis. 
