The hot issue: TOR signalling network in plants
Ying Zhao
A and Xiu-Qin Wang A B
+ Author Affiliations
- Author Affiliations
A College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
B Corresponding author. Email: wangxqbj@163.com
Functional Plant Biology 48(1) 1-7 https://doi.org/10.1071/FP20071
Submitted: 17 March 2020 Accepted: 10 August 2020 Published: 10 September 2020
Abstract
The target of rapamycin (TOR) signalling network plays a pivotal role in regulating sugar metabolism and life-span in yeast, plants and mammals, in which TOR functions as a crucial protein. In plants, the TOR complex comprises TOR, RAPTOR (regulatory-associated protein of TOR) and LST8 (lethal with SEC13 protein 8). Factors like light, auxin, glucose, sucrose and amino acid can activate TOR protein as upstream signals to further phosphorylate downstream factors of TOR which promote cell proliferation and growth in plants. In this review, we analyse the TOR signalling network in plants and discuss the relationship between glucose and TOR, as well as the dynamic balance between TOR and sucrose-non-fermenting-related protein kinases (SnRKs). Given that 63 novel TOR-regulated proteins have been identified in previous studies, we also believe there are many unknown functions of TOR that need to be further investigated.
Additional keywords: glucose, signalling network, sucrose-non-fermenting-related protein kinases, sugar metabolism, target of rapamycin.
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