An economic point of view of secondary compounds in halophytes
Anne Buhmann A and Jutta Papenbrock A B
+ Author Affiliations
- Author Affiliations
A Institute of Botany, Leibniz University Hannover, 30419 Hannover, Germany.
B Corresponding author. Email: jutta.papenbrock@botanik.uni-hannover.de
This paper originates from a presentation at the COST WG2 Meeting ‘Putting halophytes to work – genetics, biochemistry and physiology’ Hannover, Germany, 28–31 August 2012.
Functional Plant Biology 40(9) 952-967 https://doi.org/10.1071/FP12342
Submitted: 11 November 2012 Accepted: 22 February 2013 Published: 21 March 2013
Abstract
Salt tolerance of halophytes relies on several strategies, among them, the production of species-specific secondary metabolites. Chemically, a broad variety of secondary compounds of economic interest is present in halophytes. Several of these secondary compounds are restricted to halophytic species or are found in higher concentrations than in glycophytes. For their exploitation, optimal plant cultivation conditions and extraction, fractionation and isolation processes need to be identified. On the one hand, the function of single compounds can be more precisely determined and controlled; on the other hand the mixture of compounds in crude extracts might have synergistic effects. Also, different plant organs and plants in different developmental stages contain highly varying amounts and compositions of secondary compounds. Secondary compounds from halophytes have potential uses in various fields such as pharmacognosy, functional foods, nutraceuticals and technical implementations. Many of the potential applications are still in the research and development phase; some products are already on the market. We describe and evaluate the economic potential of several halophytes such as Salicornia spp. and Crithmum maritimum containing valuable compounds used in different applications.
Additional keywords: Nutraceuticals, oxidative stress, pharmacology, Salicornia, salinity, technical applications.
References
Ainsworth EA, Gillespie KM (2007) Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent. Nature Protocols 2, 875–877.| Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXhtFGnur%2FN&md5=1dd06a5b68f5a087638341a0905f354fCAS |
Aquino RS, Grativol C, Mourão PA (2011) Rising from the sea: correlations between sulfated polysaccharides and salinity in plants. PLoS ONE 6, e18862
| Rising from the sea: correlations between sulfated polysaccharides and salinity in plants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXls1Kku78%3D&md5=8b715253f429131859ff12474333da1aCAS |
Aronson JA (1989) HALOPH: a data base of salt tolerant plants of the world. (Arid Land Studies, University of Arizona: Tucson, AZ)
Atia A, Debez A, Barhoumi Z, Abdelly C, Smaoui A (2010) Localization and composition of seed oils of Crithmum maritimum L. (Apiaceae). African Journal of Biotechnology 9, 6482–6485.
Atia A, Barhoumi Z, Mokded R, Abdelly C, Smaoui A (2011) Environmental eco-physiology and economical potential of the halophyte Crithmum maritimum L. (Apiaceae). Journal of Medicinal Plants Research 5, 3564–3571.
Barrios CA, Xu Q, Cutright T, Newby BM (2005) Incorporating zosteric acid into silicone coatings to achieve its slow release while reducing fresh water bacterial attachment. Colloids and Surfaces. B, Biointerfaces 41, 83–93.
| Incorporating zosteric acid into silicone coatings to achieve its slow release while reducing fresh water bacterial attachment.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXhvVCgsb0%3D&md5=92fb17241b0f19da156f02082b273c1bCAS |
Benhammou N, Bekkara FA, Panovska TK (2009) Antioxidant activity of methanolic extracts and some bioactive compounds of Atriplex halimus. Comptes Rendus. Chimie 12, 1259–1266.
| Antioxidant activity of methanolic extracts and some bioactive compounds of Atriplex halimus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhsFWmu77E&md5=01043180c4e34a0af9d947c5dbd9fc08CAS |
BOSTID (1990) ‘Saline agriculture: salt-tolerant plants for developing countries.’ (National Academy Press: Washington, DC)
Bouayed J, Bohn T (2010) Exogenous antioxidants – double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxidative Medicine and Cellular Longevity 3, 228–237.
| Exogenous antioxidants – double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses.Crossref | GoogleScholarGoogle Scholar |
Bouftira I, Abdelly C, Sfar S (2007) Identification of a naturally occurring 2,6-bis (1,1-dimethylethyl)-4-methylphenol from purple leaves of the halophyte plant Mesembryanthemum crystallinum. African Journal of Biotechnology 6, 1136–1139.
Bouftira I, Abdelly C, Sfar S (2008) Characterization of cosmetic cream with Mesembryanthemum crystallinum plant extract: influence of formulation composition on physical stability and anti-oxidant activity. International Journal of Cosmetic Science 30, 443–452.
| Characterization of cosmetic cream with Mesembryanthemum crystallinum plant extract: influence of formulation composition on physical stability and anti-oxidant activity.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD1M%2FgslChsw%3D%3D&md5=13657b3023ead0698085b3873b6d630cCAS |
Bouftira I, Al Hajari S, Abdelly C, Sfar S (2010) Antioxidative and free radical of Limonium axillare from qatarian coasts. WebmedCentral. Pharmaceutical Sciences 1, WMC00570
Boughalleb F, Denden M (2011) Physiological and biochemical changes of two halophytes, Nitraria retusa (Forssk.) and Atriplex halimus (L.) under increasing salinity. Agricultural Journal 6, 327–339.
| Physiological and biochemical changes of two halophytes, Nitraria retusa (Forssk.) and Atriplex halimus (L.) under increasing salinity.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XktV2jsLk%3D&md5=e38384233e23273b5473ffa1562290ecCAS |
Boughalleb N, Trabelsi L, Harzallah-Skhiri F (2009) Antifungal activity from polar and non-polar extracts of some Chenopodiaceae wild species growing in Tunisia. Natural Product Research 23, 988–997.
| Antifungal activity from polar and non-polar extracts of some Chenopodiaceae wild species growing in Tunisia.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXos1CqtLw%3D&md5=ecb445f64e985671d8944951844e53eeCAS |
Chandrasekaran M, Senthilkumar A, Venkatesalu V (2011) Antibacterial and antifungal efficacy of fatty acid methyl esters from the leaves of Sesuvium portulacastrum L. European Review for Medical and Pharmacological Sciences 15, 775–780.
Charnoc A (1988) Plants with a taste for salt. New Scientist 3, 41–45.
Chaudhary S, Khosa RL, Priyank , Rani S (2012) A report on pharmacognostical and quality control parameters of stem and root of Cressa cretica Linn, Convolvulaceae. Journal of Pharmacy Research 5, 616–621.
Chung YC, Chun HK, Yang JY, Kim JY, Han EH, Kho YH, Jeong HG (2005) Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea. Archives of Pharmacal Research 28, 1122–1126.
| Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXht1Wrur3O&md5=5d023e357b4920ca347299bf0747e10dCAS |
Chung YC, Choi JH, Oh KN, Chun HK, Jeong HG (2006) Tungtungmadic acid isolated form Salicornia herbacea suppresses the progress of carbon tetrachloride-induced hepatic fibrosis in mice. Journal of Toxicology and Public Health 22, 267–273.
Custódio L, Ferreira AC, Pereira H, Silvestre L, Vizetto-Duarte C, Barreira L, Rauter AP, Alberício F, Varela J (2012) The marine halophytes Carpobrotus edulis L. and Arthrocnemum macrostychyum L. are potential sources of nutritionally important PUFAs and metabolites with antioxidant, metal chelating and anticholinesterase inhibitory activities. Botanica Marina 55, 281–288.
| The marine halophytes Carpobrotus edulis L. and Arthrocnemum macrostychyum L. are potential sources of nutritionally important PUFAs and metabolites with antioxidant, metal chelating and anticholinesterase inhibitory activities.Crossref | GoogleScholarGoogle Scholar |
Dewanto VX, Wu K, Adom K, Liu RH (2002) Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. Journal of Agricultural and Food Chemistry 50, 3010–3014.
| Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XivVGns7c%3D&md5=85e3a79a7725e2ae64957c432afa7ebfCAS |
Dubois V, Breton S, Linder M, Fanni J, Parmentier M (2007) Fatty acid profiles of 80 vegetable oils with regard to their nutritional potential. European Journal of Lipid Science and Technology 109, 710–732.
| Fatty acid profiles of 80 vegetable oils with regard to their nutritional potential.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXovFalsLo%3D&md5=03dcf66d82baeea903718f6eb5c3511fCAS |
Dudonné S, Vitrac X, Coutière P, Woillez M, Mérillon JM (2009) Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD, and ORAC assays. Journal of Agricultural and Food Chemistry 57, 1768–1774.
| Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD, and ORAC assays.Crossref | GoogleScholarGoogle Scholar |
Endale M, Song JC, Rhee MH, Liu K-H, Kim T-K, Kwon JG, Park KS, Chung K-M, Kim TW (2011) Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by β-adrenoceptor. Laboratory Animal Research 27, 317–325.
| Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by β-adrenoceptor.Crossref | GoogleScholarGoogle Scholar |
Espín JC, Garcia-Conesa MT, Tomas-Barberan FA (2007) Nutraceuticals: facts and fiction. Phytochemistry 68, 2986–3008.
| Nutraceuticals: facts and fiction.Crossref | GoogleScholarGoogle Scholar |
Falleh H, Ksouri R, Chaieb K, Karray-Bouraoui N, Trabelsi N, Boulaaba M, Abdelly C (2008) Phenolic composition of Cynara cardunculus L. organs, and their biological activities. Comptes Rendus Biologies 331, 372–379.
| Phenolic composition of Cynara cardunculus L. organs, and their biological activities.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXlslynu7Y%3D&md5=aae63e1a60f62f4e4a5ece4599149d98CAS |
Falleh H, Ksouri R, Oueslati S, Guyot S, Magné C, Abdelly C (2009) Interspecific variability of antioxidant activities and phenolic composition in Mesembryanthemum genus. Food and Chemical Toxicology 47, 2308–2313.
| Interspecific variability of antioxidant activities and phenolic composition in Mesembryanthemum genus.Crossref | GoogleScholarGoogle Scholar |
Falleh H, Ksouri R, Medini F, Guyot S, Abdelly C, Magné C (2011a) Antioxidant activity and phenolic composition of the medicinal and edible halophyte Mesembryanthemum edule L. Industrial Crops and Products 34, 1066–1071.
| Antioxidant activity and phenolic composition of the medicinal and edible halophyte Mesembryanthemum edule L.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXnsFSqt78%3D&md5=463f448e428a1b885c3e073e6cc9d926CAS |
Falleh H, Oueslati S, Guyot S, Ben Dali A, Magné C, Abdelly C, Ksouri R (2011b) LC/ESI-MS/MS characterisation of procyanidins and propelargonidins responsible for the strong antioxidant activity of the edible halophyte Mesembryanthemum edule L. Food Chemistry 127, 1732–1738.
| LC/ESI-MS/MS characterisation of procyanidins and propelargonidins responsible for the strong antioxidant activity of the edible halophyte Mesembryanthemum edule L.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXjvVWjsrk%3D&md5=63f31c02c9eb57862513d820de7b600cCAS |
Falleh H, Ksouri R, Boulaaba M, Guyot S, Abdelly C, Magné C (2012) Phenolic nature, occurrence and polymerization degree as marker of environmental adaptation in the edible halophyte Mesembryanthemum edule. South African Journal of Botany 79, 117–124.
| Phenolic nature, occurrence and polymerization degree as marker of environmental adaptation in the edible halophyte Mesembryanthemum edule.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XksFantLg%3D&md5=10ebdebe203ac46605423efd2398d8fdCAS |
Falleh H, Trabelsi N, Bonenfant-Magné M, Le Floch G, Abdelly C, Magné C, Ksouri R (2013) Polyphenol content and biological activities of Mesembryanthemum edule organs after fractionation. Industrial Crops and Products 42, 145–152.
| Polyphenol content and biological activities of Mesembryanthemum edule organs after fractionation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38Xht1entLvM&md5=bbda843ca72aeef2f8353f90329ecaffCAS |
Flowers T, Colmer T (2008) Salinity tolerance in halophytes. New Phytologist 179, 945–963.
| Salinity tolerance in halophytes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhtFWqur%2FE&md5=06dcabcbf1411c34a35d7aed78f04afbCAS |
Flowers T, Troke PF, Yeo AR (1977) The mechanism of salt tolerance in halophytes. Annual Review of Plant Physiology 28, 89–121.
| The mechanism of salt tolerance in halophytes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaE2sXksFSisb8%3D&md5=ab0a16957d0ffbee896436c71cd4eb84CAS |
Flückiger FA, Tschirch A (1885) ‘Grundlagen der Pharmacognosie: Einleitung in das Studium der Rohstoffe des Pflanzenreiches.’ 2nd edn. (Springer-Verlag: Berlin)
Glenn EP, Brown JJ, Blumwald E (1999) Salt tolerance and crop potential of halophytes. Critical Reviews in Plant Sciences 18, 227–255.
| Salt tolerance and crop potential of halophytes.Crossref | GoogleScholarGoogle Scholar |
Gong Q, Li P, Ma S, Indu Rupassara S, Bohnert HJ (2005) Salinity stress adaptation competence in the extremophile Thellungiella halophila in comparison with its relative Arabidopsis thaliana. The Plant Journal 44, 826–839.
| Salinity stress adaptation competence in the extremophile Thellungiella halophila in comparison with its relative Arabidopsis thaliana.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXhtlWltrbN&md5=620030b0bcdb8cf64087da8a830c4207CAS |
Guil-Guerrero JL, Rodríguez-Gercía I (1999) Lipid classes, fatty acids and carotenes of the leaves of six edible wild plants. European Food Research and Technology 209, 313–316.
| Lipid classes, fatty acids and carotenes of the leaves of six edible wild plants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1MXlvVyrtL4%3D&md5=18c69d2d3a6b54a271d639bb1f5c3c42CAS |
Habiba U, Bose U, Rahman AA (2010) Antinociceptive, antidiarrhoeal and cytotoxic activity of Tamarix indica leaf. Pharmacologyonline 1, 275–283.
Hafsi C, Romero-Puertas MC, Gupta DK, del Río LA, Sandalio LM, Abdelly C (2010) Moderate salinity enhances the antioxidative response in the halophyte Hordeum maritimum L. under potassium deficiency. Environmental and Experimental Botany 69, 129–136.
| Moderate salinity enhances the antioxidative response in the halophyte Hordeum maritimum L. under potassium deficiency.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXmtFant7Y%3D&md5=484148a3798ce899ab54afc91f144963CAS |
Hagihara M, Takei A, Ishii T, Hayashi F, Kubota K, Wakamatsu K, Nameki N (2012) Inhibitory effects of choline-O-sulfate on amyloid formation of human isletamyloid polypeptide. FEBS Open Bio 2, 20–25.
| Inhibitory effects of choline-O-sulfate on amyloid formation of human isletamyloid polypeptide.Crossref | GoogleScholarGoogle Scholar |
Harrison PG (1982) Control of microbial growth and of amphipod grazing by water-soluble compounds from leaves of Zostera marina. Marine Biology 67, 225–230.
| Control of microbial growth and of amphipod grazing by water-soluble compounds from leaves of Zostera marina.Crossref | GoogleScholarGoogle Scholar |
Harrison PG (1989) Detrital processing in seagrass systems: a review of factors affecting decay rates, remineralization and detritivory. Aquatic Botany 35, 263–288.
| Detrital processing in seagrass systems: a review of factors affecting decay rates, remineralization and detritivory.Crossref | GoogleScholarGoogle Scholar |
Hwang Y, Yun H, Chun H, Chung Y, Kim H, Jeong M, Yoon T, Jeong H (2009) Protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from Salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage. Chemico-Biological Interactions 181, 366–376.
| Protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from Salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhtFGksrzF&md5=3191a456b93120da447c2cd29a7874f2CAS |
Ibdah M, Krins A, Seidlitz HK, Heller W, Strack D, Vogt T (2002) Spectral dependence of flavonol and betacyanin accumulation in Mesembryanthemum crystallinum under enhanced ultraviolet radiation. Plant, Cell & Environment 25, 1145–1154.
| Spectral dependence of flavonol and betacyanin accumulation in Mesembryanthemum crystallinum under enhanced ultraviolet radiation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XnvVWitL8%3D&md5=424784b69551e81e71f882b88f6773dcCAS |
Iso H, Sato S, Umemura U, Kudo M, Koike K, Kitamura A, Imano H, Okamura T, Naito Y, Shimamoto T (2002) Linoleic acid, other fatty acids, and the risk of stroke. Stroke 33, 2086–2093.
| Linoleic acid, other fatty acids, and the risk of stroke.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XmvVeisrw%3D&md5=77c6f720401ab2a88b65c2f536697e55CAS |
IUCN (2005) ‘A guide to medicinal plants in North Africa.’ (IUCN Centre for Mediterranean Cooperation: Malaga, Spain)
Ivanova A, Nechev J, Tsvetkova I, Stefanov K, Popov S (2009) Chemical composition of the halophyte plant Stachys maritime Gouan from the Bulgarian Black Sea coast. Natural Product Research 23, 448–454.
| Chemical composition of the halophyte plant Stachys maritime Gouan from the Bulgarian Black Sea coast.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXlsVWlsLY%3D&md5=e74347e0584348e6c76b78e84795efc1CAS |
Jallali I, Megdiche W, M’Hamdi B, Oueslati S, Smaoui A, Abdelly C, Ksouri R (2012) Changes in phenolic composition and antioxidant activities of the edible halophyte Crithmum maritimum L. with physiological stage and extraction method. Acta Physiologiae Plantarum 34, 1451–1459.
| Changes in phenolic composition and antioxidant activities of the edible halophyte Crithmum maritimum L. with physiological stage and extraction method.Crossref | GoogleScholarGoogle Scholar |
Jung HA, Park JJ, Islam MN, Jin SE, Min B-S, Lee J-H, Sohn HS, Choi JS (2012) Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation. Archives of Pharmacal Research 35, 1021–1035.
| Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XpsVOrsr8%3D&md5=d7b1941dbe5f4a196209b6be4465080bCAS |
Kadereit G, Ball P, Beer S, Mucina L, Sokoloff D, Teege P, Yaprak AE, Freitag H (2007) A taxonomic nightmare comes true: phylogeny and biogeography of glassworts (Salicornia L., Chenopodiaceae). Taxon 56, 1143–1170.
| A taxonomic nightmare comes true: phylogeny and biogeography of glassworts (Salicornia L., Chenopodiaceae).Crossref | GoogleScholarGoogle Scholar |
Kang S, Kim D, Lee BH, Kim MR, Chiang M, Hong J (2011) Antioxidant properties and cytotoxic effects of fractions from glasswort (Salicornia herbacea) seed extracts on human intestinal cells. Food Science and Biotechnology 20, 115–122.
| Antioxidant properties and cytotoxic effects of fractions from glasswort (Salicornia herbacea) seed extracts on human intestinal cells.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXisVKlu7c%3D&md5=da04fd150154f7a108b34bb38a369e5cCAS |
Kassing M, Strube J (2012) ‘Process development for plant-based extract production.’ (Shaker-Verlag: Aachen, Germany)
Kassing M, Jenelten U, Schenk J, Strube S (2010) A new approach for process development of plant-based extraction processes. Chemical Engineering & Technology 33, 377–387.
| A new approach for process development of plant-based extraction processes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXis1enu70%3D&md5=4840d6113ff5137f570b2de5d47abe4cCAS |
Kefu Z, Hai F, Ungar IA (2002) Survey of halophyte species in China. Plant Science 163, 491–498.
| Survey of halophyte species in China.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XntVejtL8%3D&md5=0b10d7e3825a40048bde9579d404aeddCAS |
Khan AM, Ungar IA, Showalter AM, Dewald HD (1998) NaCl-induced accumulation of glycinebetain in four subtropical halophytes from Pakistan. Physiologia Plantarum 102, 487–492.
| NaCl-induced accumulation of glycinebetain in four subtropical halophytes from Pakistan.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1cXjs1yqsb4%3D&md5=9708cf7f268133a7c3f79c22337a4661CAS |
Kim NM, Kim J, Chung HY, Choi JS (2000) Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana. Archives of Pharmacal Research 23, 237–239.
| Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3cXkvFGitbg%3D&md5=b569176b5d32832fae8997fc147a989eCAS |
Kim YA, Kong C-S, Lee JI, Kim H, Park HY, Lee H-S, Le C, Seo Y (2012) Evaluation of novel antioxidant triterpenoid saponins from the halophyte Salicornia herbacea. Bioorganic & Medicinal Chemistry Letters 22, 4318–4322.
| Evaluation of novel antioxidant triterpenoid saponins from the halophyte Salicornia herbacea.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XnvVyktbY%3D&md5=ae28422416bf755aea4756ae51f7a3f7CAS |
Kong C-S, Kim J-A, Qian Z-J, Kim YA, Lee JI, Kim S-K, Namd TJ, Seo Y (2009) Protective effect of isorhamnetin 3-O-β-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage. Food and Chemical Toxicology 47, 1914–1920.
| Protective effect of isorhamnetin 3-O-β-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXosV2gsbY%3D&md5=467a28f1dbc8d4b0f8891125c715d9c1CAS |
Kong C-S, Lee JI, Kim YA, Kim J-A, Bak SS, Hong JW, Park HY, Yea SS, Seo Y (2012) Evaluation on anti-adipogenic activity of flavonoid glucopyranosides from Salicornia herbacea. Process Biochemistry 47, 1073–1078.
| Evaluation on anti-adipogenic activity of flavonoid glucopyranosides from Salicornia herbacea.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XlvFyisrc%3D&md5=e436ea4dc4a457147765e97ba43fb3edCAS |
Ksouri R, Megdiche W, Debez A, Falleh H, Grignon C, Abdelly C (2007) Salinity effects on polyphenol content and antioxidant activities in leaves of the halophyte Cakile maritima. Plant Physiology and Biochemistry 45, 244–249.
| Salinity effects on polyphenol content and antioxidant activities in leaves of the halophyte Cakile maritima.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXkslCiu70%3D&md5=f869c0e7a0889e3ab2697f6b416a33f6CAS |
Ksouri R, Megdiche W, Falleh H, Trabelsi N, Boulaaba M, Smaoui A, Abdelly C (2008) Influence of biological, environmental and technical factors on phenolic content and antioxidant activities of Tunesian halophytes. Comptes Rendus Biologies 331, 865–873.
| Influence of biological, environmental and technical factors on phenolic content and antioxidant activities of Tunesian halophytes.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXht1Knur%2FK&md5=fcfde6c3922e0934c040a905d1ebf42bCAS |
Ksouri R, Falleh H, Megdiche W, Trabelsi N, Mhamdi B, Chaieb K, Bakrouf A, Magné C, Abdelly C (2009) Antioxidant and antimicrobial activities of the edible medicinal halophyte Tamarix gallica L. and related polyphenolic constituents. Food and Chemical Toxicology 47, 2083–2091.
| Antioxidant and antimicrobial activities of the edible medicinal halophyte Tamarix gallica L. and related polyphenolic constituents.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXosV2gtLo%3D&md5=92722c47facafb8ca3b6f59a61794106CAS |
Ksouri R, Ksouri WM, Jallali I, Debez A, Magné C, Hiroko I, Abdelly C (2012) Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications. Critical Reviews in Biotechnology 32, 289–326.
Kumar SR, Ramanathan G, Subhakaran M, Inbaneson SJ (2009) Antimicrobial compounds from marine halophytes for silkworm disease treatment. International Journal of Medicine and Medical Sciences 5, 184–191.
Kurosu M, Kazuichi S (2011) Mesembryanthemum crystallinum extract suppressed the early differentiation of mouse 3T3–L1 preadipocytes. Journal of Natural Pharmaceuticals 2, 184–189.
| Mesembryanthemum crystallinum extract suppressed the early differentiation of mouse 3T3–L1 preadipocytes.Crossref | GoogleScholarGoogle Scholar |
Lee JI, Kong C-S, Jung ME, Hong JW, Lim SY, Seo Y (2011) Antioxidant activity of the halophyte Limonium tetragonum and its major active components. Biotechnology and Bioprocess Engineering 16, 992–999.
| Antioxidant activity of the halophyte Limonium tetragonum and its major active components.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXht1agtbzP&md5=5b03ff21fdbec2ec37691ef74e690a53CAS |
Lellau TF, Liebezeit G (2003) Activity of ethanolic extracts of salt marsh plants from the Lower Saxonian Wadden Sea coast against microorganisms. Senckenbergiana maritima 32, 177–181.
| Activity of ethanolic extracts of salt marsh plants from the Lower Saxonian Wadden Sea coast against microorganisms.Crossref | GoogleScholarGoogle Scholar |
Liebezeit G (2008) Ethnobotany and phytochemistry of plants dominant in salt marshes of the Lower Saxonian Wadden Sea, southern North Sea. Senckenbergiana maritime 38, 1–30.
| Ethnobotany and phytochemistry of plants dominant in salt marshes of the Lower Saxonian Wadden Sea, southern North Sea.Crossref | GoogleScholarGoogle Scholar |
Liebezeit G, Künnemann TD, Gad G (1999) Biotechnological potential of North Sea salt marsh plants – a review of traditional knowledge. Journal of Biotechnology 70, 77–84.
| Biotechnological potential of North Sea salt marsh plants – a review of traditional knowledge.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1MXjs1Shs78%3D&md5=bf9f97fe51aef7136c11bc204d6b9621CAS |
Manikandan T, Neelakandan T, Rani GU (2009) Antibacterial activity of Salicornia brachiata, a halophyte. Journal of Phytology 1, 441–443.
Medini F, Ksouri R, Falleh H, Megdiche W, Trabelsi N, Abdelly C (2011) Effects of physiological stage and solvent on polyphenol composition, antioxidant and antimicrobial activities of Limonium densiflorum. Journal of Medicinal Plants Research 5, 6719–6730.
Megdiche KW, Chaouachi F, M’Rabet R, Medini F, Zaouali Y, Trabelsi N, Ksouri R, Noumi E, Abdelly C (2011) Antioxidant and antimicrobial properties of Frankenia thymifolia Desf. fractions and their related biomolecules identification by gas chromatography/mass spectrometry (GC/MS) and high performance liquid chromatography (HPLC). Journal of Medicinal Plants Research 5, 5754–5765.
Meot-Duros L, Magné C (2009) Antioxidant activity and phenol content of Crithmum maritimum L. leaves. Plant Physiology and Biochemistry 47, 37–41.
| Antioxidant activity and phenol content of Crithmum maritimum L. leaves.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhsFamtbnL&md5=4cfefe47d7f571649b7c3c9b96e0f2d8CAS |
Meot-Duros L, Cératola S, Talarmin H, Le Meur C, Le Floch G, Magné C (2010) New antibacterial and cytotoxic activities of falcarindiol isolated in Crithmum maritimum L. leaf extract. Food and Chemical Toxicology 48, 553–557.
| New antibacterial and cytotoxic activities of falcarindiol isolated in Crithmum maritimum L. leaf extract.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXhtlKrur0%3D&md5=0f849a363d78ca38ae1788432e919bd5CAS |
Molina RV, Valero M, Navarro Y, Guardiola JL, Garcia-Luis A (2005) Temperature effects on flowering formation in saffron (Crocus sativus L.). Scientia Horticulturae 103, 361–379.
| Temperature effects on flowering formation in saffron (Crocus sativus L.).Crossref | GoogleScholarGoogle Scholar |
Ninfali P, Mea G, Giorgini S, Rocchi M, Bacchiocca M (2005) Antioxidant capacity of vegetables, spices and dressings relevant to nutrition. British Journal of Nutrition 93, 257–266.
| Antioxidant capacity of vegetables, spices and dressings relevant to nutrition.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXivVCktrw%3D&md5=0a69b5cbd2a473a3a46dcdd584ad0cf4CAS |
Nostro A, Filocamo A, Giovannini A, Catania S, Costa C, Marino A, Bisignano G (2011) Antimicrobial activity and phenolic content of natural site and micropropagated Limonium avei (De Not.) Brullo & Erben plant extracts. Natural Product Research: Formerly Natural Product Letters
| Antimicrobial activity and phenolic content of natural site and micropropagated Limonium avei (De Not.) Brullo & Erben plant extracts.Crossref | GoogleScholarGoogle Scholar |
Orfali RS (2005) Phytochemical and biological study of Tamarix nilotica growing in Saudi Arabia. Masters thesis, Department of Pharmacognosy at the College of Pharmacy, King Saud University.
Oueslati S, Ksouri R, Falleh H, Pichette A, Abdelly C, Legault J (2012) Phenolic content, antioxidant, anti-inflammatory and anticancer activities of the edible halophyte Suaeda fruticosa Forssk. Food Chemistry 132, 943–947.
| Phenolic content, antioxidant, anti-inflammatory and anticancer activities of the edible halophyte Suaeda fruticosa Forssk.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhs1Kru77J&md5=a0db7865c7d4b591a3f291d0b9da7d6dCAS |
Rele S, Banerji A, Chintalwar G, Kumar V, Yadava V (2003) A new conformer of 20-hydroxyecdysone from Sesuvium portulacastrum: an X-ray crystallographic study. Natural Product Research 17, 103–108.
| A new conformer of 20-hydroxyecdysone from Sesuvium portulacastrum: an X-ray crystallographic study.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXjtValtLw%3D&md5=ec6be21b27c977675d7ede7bdfa21050CAS |
Rhee MH, Park HJ, Cho JY (2009) Salicornia herbacea: Botanical, chemical and pharmacological review of halophyte marsh plant. Journal of Medicinal Plants Research 3, 548–555.
Rozema J, Flowers T (2008) Crops for a salinized world. Science 322, 1478–1480.
| Crops for a salinized world.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhsFSisr%2FM&md5=69a14a68a0adf99a318e046a7d153db2CAS |
Ryu D, Kim S, Lee D (2009) Anti-proliferative effect of polysaccharides from Salicornia herbacea on induction of G2/M arrest and apoptosis in human colon cancer cells. Journal of Microbiology and Biotechnology 19, 1482–1489.
| Anti-proliferative effect of polysaccharides from Salicornia herbacea on induction of G2/M arrest and apoptosis in human colon cancer cells.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXlvVWkug%3D%3D&md5=352b73c8d74a27cb3ef101985f7dc637CAS |
Saidana D, Halima-Kamel MB, Mahjoub MA, Haouas D, Mighri Z, Helal AN (2007) Insecticidal activities of Tunisian halophytic plant extracts against larvae and adults of Tribolium confusum. Tropicultura 25, 193–199.
Saidana D, Mahjoub S, Boussaada O, Chriaa J, Mahjoub MA, Chéraif I, Daami M, Mighri Z, Helal AN (2008) Antibacterial and antifungal activities of the essential oils of two saltcedar species from Tunisia. Journal of the American Oil Chemists’ Society 85, 817–826.
Samiullah AB, Naz R, Yasmin H (2011) In vitro inhibition potential of Lespedeza bicolour Turcz against selected bacterial and fungal strains. Journal of Medicinal Plants Research 5, 3708–3714.
Sanchez DH, Siahpoosh MR, Roessner U, Udvardi M, Kopka J (2008) Plant metabolomics reveals conserved and divergent metabolic responses to salinity. Physiologia Plantarum 132, 209–219.
Singleton VL, Rossi JA (1965) Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American Journal of Enology and Viticulture 16, 144–158.
Siracusa L, Kulisic-Bilusic T, Politeo O, Krause I, Dejanovic B, Ruberto G (2011) Phenolic composition and antioxidant activity of aqueous infusions from Capparis spinosa L. and Crithmum maritimum L. before and after submission to a two step in vitro digestion model. Journal of Agricultural and Food Chemistry 59, 12453–12459.
| Phenolic composition and antioxidant activity of aqueous infusions from Capparis spinosa L. and Crithmum maritimum L. before and after submission to a two step in vitro digestion model.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXhtlGjt7jP&md5=278bcc9f12808117019c47905537debdCAS |
Sun B, Richardo-da-Silvia JM, Spranger I (1998) Critical factors of vanillin assay for catechins and proanthocyanidins. Journal of Agricultural and Food Chemistry 46, 4267–4274.
| Critical factors of vanillin assay for catechins and proanthocyanidins.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1cXmtFakur0%3D&md5=aa92bfb7b84bd59aef37791696d5a941CAS |
Sung JH, Park SH, Seo DH, Lee JH, Hong SW, Hong SS (2009) Antioxidative and skin-whitening effect of an aqueous extract of Salicornia herbacea. Bioscience, Biotechnology, and Biochemistry 73, 552–556.
| Antioxidative and skin-whitening effect of an aqueous extract of Salicornia herbacea.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXksFWmt78%3D&md5=2bd40f3712d8e94c97753e082f7cb4bbCAS |
Sunita P, Jha S, Pattanayak SP, Mishra SK (2012) Antimicrobial activity of a halophytic plant Cressa cretica L. Journal of Scientific Research 4, 203–212.
Thirunavukkarasu P, Ramkumar L, Ramanathan T, Silambarasan G (2010) Antioxidant activity of selected coastal medicinal plants. World Journal of Fish and Marine Sciences 2, 134–137.
Thirunavukkarasu P, Ramanathan T, Renugadevi G, Jayalakshmi S (2011) Studies on larvicidal potential of Excoecaria agallocha L. bark extract. Journal of Pharmacy Research 4, 3480–3482.
Todd JS, Zimmerman RC, Crews P, Alberte RS (1993) The antifouling activity of natural and synthetic phenol acid sulphate esters. Phytochemistry 34, 401–404.
| The antifouling activity of natural and synthetic phenol acid sulphate esters.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK3sXms1Kmtro%3D&md5=3741d2e60c92d265ad3d1cfa9f015e3dCAS |
Trabelsi N, Megdiche W, Ksouri R, Falleh H, Oueslati S, Soumaya B, Hajlaoui H, Abdelly C (2010) Solvent effects on phenolic contents and biological activities of the halophyte Limoniastrum monopetalum leaves. LWT – Food Science and Technology 43, 632–639.
| Solvent effects on phenolic contents and biological activities of the halophyte Limoniastrum monopetalum leaves.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXht12ntLs%3D&md5=365b95bd1d1cc7048c94b920b5c6de98CAS |
Trabelsi N, Oueslati S, Falleh H, Waffo-Téguo P, Papastamoulis Y, Mérillon J-M, Abdelly C, Ksouri R (2012) Isolation of powerful antioxidants from the medicinal halophyte Limoniastrum guyonianum. Food Chemistry 135, 1419–1424.
| Isolation of powerful antioxidants from the medicinal halophyte Limoniastrum guyonianum.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XhtlSlsr%2FP&md5=3400a8e3d79574160d071e8140f2cf16CAS |
Um YR, Kong C-S, Lee JI, Kim YA, Nam TJ, Seo Y (2010) Evaluation of chemical constituents from Glehnia littoralis for antiproliferative activity against HT-29 human colon cancer cells. Process Biochemistry 45, 114–119.
| Evaluation of chemical constituents from Glehnia littoralis for antiproliferative activity against HT-29 human colon cancer cells.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXhsVGrur%2FP&md5=f82d5d4c3bc898e001d8c603ea016882CAS |
Ventura Y, Wuddineh WA, Myrzabayeva M, Alikulov Z, Khozin-Goldberg I, Shpigel M, Samocha TM, Sagi M (2011) Effect of seawater concentration on the productivity and nutritional value of annual Salicornia and perennial Sarcocornia halophytes as leafy vegetable crops. Scientia Horticulturae 128, 189–196.
| Effect of seawater concentration on the productivity and nutritional value of annual Salicornia and perennial Sarcocornia halophytes as leafy vegetable crops.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXjtFSru7k%3D&md5=be56fe1d749de296b8c7fb14fc8353ceCAS |
Villa F, Albanese D, Giussani B, Stewart PS, Daffonchio D, Cappitelli F (2010) Hindering biofilm formation with zosteric acid. Biofouling 26, 739–752.
| Hindering biofilm formation with zosteric acid.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXhtVansb7E&md5=355c39ff524d92191f8cf2daf5daa758CAS |
Wang L, Zhao Z-Y, Zhang K, Tian C-Y (2012) Oil content and fatty acid composition of dimorphic seeds of desert halophyte Suaeda aralocaspica. African Journal of Agricultural Research 7, 1910–1914.
Weber DJ, Ansari R, Gul B, Khan MA (2007) Potential of halophytes as source of edible oil. Journal of Arid Environments 68, 315–321.
| Potential of halophytes as source of edible oil.Crossref | GoogleScholarGoogle Scholar |
Williams CM (2000) Dietary fatty acids and human health. Annales de Zootechnie 49, 165–180.
| Dietary fatty acids and human health.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXnt12msr0%3D&md5=67d19e5ea95d4d46156fe786f6a229cdCAS |
Williams CM, Burdge G (2006) Long- chain n-3 PUFA: plant v. marine sources. The Proceedings of the Nutrition Society 65, 42–50.
| Long- chain n-3 PUFA: plant v. marine sources.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28Xis1aqt7k%3D&md5=0b6b84411676f028028809fd303f3f2bCAS |
Yu X, Zhang Y, Shao R, Xu W (2012) Study on antibacterial and antioxidant activities of Salicornia herbacea extracts. Advanced Materials Research 421, 47–50.
| Study on antibacterial and antioxidant activities of Salicornia herbacea extracts.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XjvFOkt7c%3D&md5=ca3ec6bfc6d513ea2a8fec8b005d52d6CAS |
Zeng GZ, Tan NH, Ji CJ, Fan JT, Huang HQ, Han HJ, Zhou GB (2009) Apoptosis inducement of bigelovin from Inula helianthus-aquatica on human Leukemia U937 cells. Phytotherapy Research 23, 885–891.
| Apoptosis inducement of bigelovin from Inula helianthus-aquatica on human Leukemia U937 cells.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXotVCjtrg%3D&md5=d322a07355ef43e0cb63188436c94f75CAS |
Zhao K, Song J, Feng G, Zhao M, Liu J (2011) Species, types, distribution, and economic potential of halophytes in China. Plant and Soil 342, 495–509.
| Species, types, distribution, and economic potential of halophytes in China.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXkslKksro%3D&md5=3f47e495ba82af40fc0a20451e6be262CAS |
