
%0 Journal Article
%A Panaretto, BA 
%T Body compostion <I>in vivo</I>. VIII. Some physiological implications with respect to extracellular fluid volume arising from the distribution of thiocyanate in sheep
%J Australian Journal of Agricultural Research
%D 1965/08/01
%V 16
%N 4
%P 667-673
%K 
%R https://doi.org/10.1071/AR9650667
%U https://www.publish.csiro.au/paper/AR9650667 
%X The distribution of [35S]-thiocyanate in sheep was studied. The specific activity in rumen fluid during the first 4 hr after injection was markedly less than in serum, and equilibration between rumen fluid and blood was not reached until 20&ndash;30 hr after injection. There were large urinary losses of the marker and approximately 50&#37; of the dose was lost in 24 hr. Activity in rumen fluid and urine was due to [35S]-thiocyanate. The thiocyanate spaces, allowing for urinary losses, during the first 4 hr after injection were 25 &ndash;30&#37; body weight, increasing to 35&ndash;40&#37; body weight at 20&ndash;30 hr after injection. The physiological implications of the results with respect to measuring extracellular fluid volume in sheep are discussed. 
