
TY  - JOUR
A1  - McCauley, I. 
A1  - Watt, M. 
A1  - Suster, D. 
A1  - Kerton, D. J. 
A1  - Oliver, W. T. 
A1  - Harrell, R. J. 
A1  - Dunshea, F. R. 
T1  - A GnRF vaccine (Improvac<emph type="2">&#174;</emph>) and porcine somatotropin (Reporcin<emph type="2">&#174;</emph>) have synergistic effects upon growth performance in both boars and gilts
JF  - Australian Journal of Agricultural Research
JO  - Aust. J.  Agric. Res.
Y1  - 2003
VL  - 54
IS  - 1
SP  - 11
EP  - 20
KW  - GnRF, feed intake, boar taint, testes, ovaries.
UR  - https://doi.org/10.1071/AR02037 
N2  - The use of a vaccine (Improvac) directed against gonadotrophin-releasing factor (GnRF), to prevent boar taint in male pigs, is also associated with an increase in feed consumption, growth, and higher deposition of subcutaneous fat. Daily administration of porcine somatotropin (pST) consistently increases average daily gain, and feed conversion efficiency, and reduces subcutaneous fat, particularly in gilts. The objective of this study was to examine the effect of combining these treatments in boars and gilts. Forty-eight pigs (Large White &#215; Landrace), housed individually, were used in a 2 &#215; 2 &#215; 2 factorial experiment with the respective factors being vaccination with GnRF vaccine (at 14 and 18 weeks of age), daily injection with pST (from 18 weeks to slaughter at 22 weeks), and sex (boars and gilts). Performance was measured over the period of pST administration. Over the entire 28 days of the study, daily gain was lower for gilts than for boars (1216 v. 1410 g/day, P &#60; 0.001), was increased by pST (1219 v. 1407 g/day, P &#60; 0.001), but not significantly altered by vaccination against GnRF (1284 v. 1342 g/day, P = 0.15). However, GnRF vaccination increased daily gain in the second 2 weeks of the study, and overall, there were interactions such that the vaccine increased gain in all groups except boars not receiving pST. Feed intake over the study period was less for gilts than for boars (3139 v. 3407 g/day, P &#60; 0.001), was decreased by pST (3537 v. 3009 g/day, P &#60; 0.001), and increased by vaccination against GnRF (3139 v. 3407 g/day, P &#60; 0.001). When averaged over the entire study, feed conversion ratio (FCR) was higher for gilts than for boars (2.76 v. 2.51, P = 0.013), was decreased by pST (3.05 v. 2.22, P &#60; 0.001), but unchanged by vaccination against GnRF (2.62 v. 2.65, P = 0.70). Fat deposition was lower in gilts than in boars (335 v. 378 g/day, P = 0.037), was decreased by pST treatment ((442 v. 271 g/day, P &#60; 0.001), and increased by vaccination against GnRF (333 v. 379 g/day, P = 0.026). In boars, fat androstenone was reduced by vaccination against GnRF (0.10 v. 2.47 &#956;g/g, P &#60; 0.001) and tended to be reduced by pST (1.71 v. 2.44, P = 0.10), but only vaccination against GnRF reduced skatole (0.174 v. 0.050 &#956;g/g, P &#60; 0.001). The combination of the treatments in all cases was at least additive, and in some cases synergistic. The concomitant vaccination against GnRF and treatment with pST affords an opportunity to increase growth rate and feed intake above control levels and above those of pigs treated with either treatment alone. 
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