Uncatalyzed Knoevenagel Condensation in PEG-600 at Room Temperature
Babasaheb P. Bandgar A B , Balaji L. Korbad A , Sachin A. Patil A , Sunita B. Bandgar A , Hemant V. Chavan A and Baliram S. Hote AA Organic Chemistry Research Laboratory, School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, India.
B Corresponding author. Email: bandgar_bp@yahoo.com
Australian Journal of Chemistry 61(9) 700-703 https://doi.org/10.1071/CH08106
Submitted: 14 March 2008 Accepted: 12 June 2008 Published: 5 September 2008
Abstract
A rapid, efficient, and ecofriendly protocol has been developed for the Knoevenagel condensation of active methylene compounds with aromatic, aliphatic, conjugated and heteroaromatic aldehydes in polyethylene glycol-600 (PEG-600) with good to excellent yields.
* The present paper is dedicated to our friend and colleague Sunita Bandgar, who passed away on 27 June 2008.
Acknowledgements
We thank the Council of Scientific and Industrial Research, New Delhi, for financial assistance (project no. 1/2023/05/EMR-II) and granting research fellowships to B.L.K., S.A.P., and B.S.H.
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