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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

An Expeditious Synthesis of Iminosugars

Michael N. Gandy A , Matthew J. Piggott A and Keith A. Stubbs A B
+ Author Affiliations
- Author Affiliations

A Chemistry M313, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.

B Corresponding author. Email: keith.stubbs@uwa.edu.au

Australian Journal of Chemistry 63(10) 1409-1412 https://doi.org/10.1071/CH10211
Submitted: 25 May 2010  Accepted: 27 July 2010   Published: 1 October 2010

Abstract

A short and expedient synthesis of the potent glycosidase inhibitors, 1-deoxynojirimycin, miglitol, miglustat, 1-deoxymannojirimycin, and 1-deoxygalactonojirimycin is presented.


References


[1]   La Ferla B., Nicotra F., in Iminosugars as Glycosidase Inhibitors: Nojirimycin and Beyond 1999, pp. 68 (Ed. A. E. Stutz) (Wiley-VCH: Weinheim).

[2]   N. Asano, R. J. Molyneaux, G. W. J. Fleet, Tetrahedron Asymmetry 2000, 11,  1645.
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