Magnetic Fe3O4 Nanoparticles as New, Efficient, and Reusable Catalysts for the Synthesis of Quinoxalines in Water
Hong-Yan Lü A , Shu-Hong Yang A , Jia Deng A and Zhan-Hui Zhang A BA The College of Chemistry and Material Science, Hebei Normal University, Shijiazhuang 050016, China.
B Corresponding author. Email: zhanhui@mail.nankai.edu.cn
Australian Journal of Chemistry 63(8) 1290-1296 https://doi.org/10.1071/CH09532
Submitted: 1 October 2009 Accepted: 31 March 2010 Published: 10 August 2010
Abstract
A novel, environmentally friendly procedure has been developed for the synthesis of quinoxaline derivatives in the presence of magnetic Fe3O4 nanoparticles. The reaction between 1,2-diamines and 1,2-dicarbonyl compounds was carried out in water to afford quinoxaline derivatives in high yield. The catalyst can be recovered by the use of an external magnet and reused for five cycles with almost consistent activity.
Acknowledgement
We are grateful for financial support from the National Natural Science Foundation of China (20872025), the Nature Science Foundation of Hebei Province (B2008000149) and the Science Foundation of Hebei Normal University (L20061314).
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