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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

An Improved and Rapid Radiochemical Method for the Determination of Polonium-210 in Urine

Elizabeth Manickam A , Sandra Sdraulig B C and Richard O’Brien B
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A School of Exercise and Nutrition Sciences, Faculty of Health, Medicine, Nursing and Behavioural Sciences, Deakin University, 221 Burwood Highway, Burwood, Vic. 3125, Australia.

B Australian Radiation Protection and Nuclear Safety Agency, 619 Lower Plenty Road, Yallambie, Vic. 3085, Australia.

C Corresponding author. Email: sandra.sdraulig@arpansa.gov.au

Australian Journal of Chemistry 63(1) 38-46 https://doi.org/10.1071/CH09118
Submitted: 27 February 2009  Accepted: 7 May 2009   Published: 8 January 2010

Abstract

Measurements of radionuclides in urine are widely used to assess the health impact of intakes of radionuclides. The events that followed the polonium poisoning in London in late 2006 have highlighted the need for rapid and reliable methods that can be applied to emergency situations. Ideally such a method would also be applicable to the routine assessment of radionuclides in urine. This paper discusses the development and validation of such a method for measuring the concentration of 210Po in urine. The method is validated by assessment of the selectivity, accuracy and recovery, and quantification of the uncertainty. The paper describes two variations of the method, based on whether the priority is a rapid turnaround, or higher sensitivity. The detection limit for the excretion rate of 210Po can range from 1.5 to 20 mBq d–1 depending on the dose limit requirements for different categories of exposure (public, occupational, or emergency).


Acknowledgements

The authors would like to acknowledge all the volunteers who took interest in the project and provided samples for measurement.


References


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