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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Efficient Synthetic Method for β-Enamino Esters Catalyzed by Yb(OTf)3 under Solvent-Free Conditions

Ravi Varala A B , Sreelatha Nuvula A and Srinivas R. Adapa A
+ Author Affiliations
- Author Affiliations

A Indian Institute of Chemical Technology, Hyderabad 500007, India.

B Corresponding author. Email: rvarala_iict@yahoo.co.in

Australian Journal of Chemistry 59(12) 921-924 https://doi.org/10.1071/CH06239
Submitted: 8 July 2006  Accepted: 8 October 2006   Published: 20 December 2006

Abstract

A wide range of β-enamino esters have been synthesized in moderate to excellent yields by reacting 1,3-dicarbonyl compounds with amines in the presence of catalytic amounts of Yb(OTf)3 (2 mol%). The reaction proceeds smoothly at ambient temperature under solvent-free conditions. The catalyst can be recovered and reused.


Acknowledgments

R.V. thanks DIICT, Dr J. S. Yadav, and Council of Scientific Industrial Research (CSIR, India) for financial support. IICT communication number 060527.


References


[1]   (a) Z. Rappoport, The Chemistry of Enamines, Part 1 1994 (John Wiley: New York, NY).
       (b) C. M. Kascheres, J. Braz. Chem. Soc. 2003, 41,  945.
         
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