A New Protocol to Synthesize Di(indolyl)pyrazolyl Methanes Using H2PtCl6 as a Catalyst in Ionic Liquid: Synthesis of Novel 3-[1H-indol-3-yl(3-phenyl-1H-pyrazol-4-yl)methyl]-1H-indoles

Rajendran Murugan; Boreddy S. R. Reddy

doi:10.1071/CH05208

RESEARCH ARTICLE

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A New Protocol to Synthesize Di(indolyl)pyrazolyl Methanes Using H₂PtCl₆ as a Catalyst in Ionic Liquid: Synthesis of Novel 3-[1H-indol-3-yl(3-phenyl-1H-pyrazol-4-yl)methyl]-1H-indoles

Rajendran Murugan ^A and Boreddy S. R. Reddy ^A ^B

+ Author Affiliations

- Author Affiliations

^A Industrial Chemistry Laboratory, Central Leather Research Institute, Adyar, Chennai 600 020, India.

^B Corresponding author. Email: induchem2000@yahoo.com

Australian Journal of Chemistry 59(4) 273-276 https://doi.org/10.1071/CH05208
Submitted: 14 August 2005 Accepted: 8 March 2006 Published: 1 May 2006

Abstract

Biologically important di(indolyl)pyrazolyl methanes and their derivatives were synthesized in excellent yields by the electrophilic substitution of indole with pyrazolyl aldehydes catalyzed by H₂PtCl₆ in ionic liquid.

Acknowledgments

R.M. thanks Dr P. T. Perumal, Organic Chemistry Laboratory, Central Leather Research Institute, Dr R. Sridhar, National University of Singapore, and E. Ramesh, University of Madras, for their help.

References

A New Protocol to Synthesize Di(indolyl)pyrazolyl Methanes Using H2PtCl6 as a Catalyst in Ionic Liquid: Synthesis of Novel 3-[1H-indol-3-yl(3-phenyl-1H-pyrazol-4-yl)methyl]-1H-indoles

Abstract

Acknowledgments

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A New Protocol to Synthesize Di(indolyl)pyrazolyl Methanes Using H₂PtCl₆ as a Catalyst in Ionic Liquid: Synthesis of Novel 3-[1H-indol-3-yl(3-phenyl-1H-pyrazol-4-yl)methyl]-1H-indoles