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RESEARCH ARTICLE
Contents Vol 57(11)

Synthesis of Methyl 2-Acetamido-2-deoxy-1-seleno-β-d-gluco- and galacto-pyranoside: Selenium Metabolites in Human Urine

Pedro Traar A , Ferdinand Belaj A and Kevin A. Francesconi A B
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- Author Affiliations

A Institute of Chemistry, Karl-Franzens-University Graz, Universitätsplatz 1, 8010 Graz, Austria.

B Corresponding author. Email: kevin.francesconi@uni-graz.at

Australian Journal of Chemistry 57(11) 1051-1053 https://doi.org/10.1071/CH04176
Submitted: 21 July 2004  Accepted: 25 August 2004   Published: 1 November 2004

Abstract

An efficient synthesis of two methyl 2-acetamido-2-deoxy-1-seleno-β-d-hexopyranosides is reported. The synthesized compounds, which have recently been identified in human urine, will be used in further studies on the metabolism and toxicology of selenium.


Acknowledgments

Olaf Kunert and Klaus Zangger are gratefully thanked for advice on NMR spectroscopy, and Rudolf Pietschnig for measuring 77Se NMR spectra. Doris Kühnelt is thanked for kindly arranging the mass spectrometric data.


References


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