
%0 Journal Article
%A Chai, CLL 
%A Hockless, DCR 
%A King, AR 
%T Reactivities of Piperazine-2,5-diones in Radical Bromination Reactions
%J Australian Journal of Chemistry
%D 1996/11/01
%V 49
%N 11
%P 1229-1233
%K 
%R https://doi.org/10.1071/CH9961229
%U https://www.publish.csiro.au/paper/CH9961229 
%X The reactivities of various N,N'- diacetylated piperazine-2,5-diones towards radical bromination reactions are reported. The studies show that glycyl  centres of piperazine-2,5-diones are more reactive towards radical bromination reactions compared to &#945;-substituted amino acid centres. In addition, large differences in reactivities were observed for the cis and trans isomers of N,N'-diacetylated alanine anhydride. Single-crystal structure determination of each isomer revealed that conformational effects may account for the difference in chemical reactivity. 
