
TY  - JOUR
A1  - Hendrickson, K 
A1  - Easton, CJ 
A1  - Lincoln, SF 
T1  - Cyclodextrin and Termethylated Cyclodextrin Complexation of Aromatic Carboxylic Acids and Their Conjugate Bases in Aqueous Solution: the Effect of Size, Hydrophobicity and Charge
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1995
VL  - 48
IS  - 6
SP  - 1125
EP  - 1132
KW  - 
UR  - https://doi.org/10.1071/CH9951125 
N2  - For &#945;- cyclodextrin ( &#945;CD ), the complexation constants (K) for the formation of binary host-guest complexes ( HA.&#945;CD ) are 750±60, 1070±60, 27±3 and 17±4 dm3 mol-1 when the guests (HA) are benzoic, 4-methylbenzoic and (R)- and (S)-2-phenylpropanoic acids, respectively, as determined by potentiometric titration in aqueous solution at 298.2 K and I = 0.10 mol dm-3 ( KCl ). For the analogous hexakis (2,3,6-tri-O-methyl)-&#945;- cyclodextrin complexes ( HA.TM&#945;CD ), K = 1580±150, 2890±130, 220±10 and 207±8 dm3 mol-1, and for the heptakis (2,3,6-tri-O-methyl)-&#946;-cyclodextrin complexes ( HA.TM&#945;CD ), K = 200±20, 340±30, 129±5 and 170±10 dm3 mol-1. The binary complexes formed by the corresponding carboxylates (A-) are much less stable. Ternary host-guest &#945;- cyclodextrin complexes (HA.&#945;CD2) are also formed. These data, together with literature data for &#946;- cyclodextrin, are discussed in terms of the factors influencing complexation. 
ER  -

