
TY  - JOUR
A1  - Cambie, RC 
A1  - Rutledge, PS 
A1  - Stevenson, RJ 
A1  - Woodgate, PD 
T1  - Synthesis of Phthalide Derivatives of Podocarpic Acid Via Directed <I>ortho</I> Metalation: a Route to Highly Substituted Octahydrochrysene Derivatives
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1994
VL  - 47
IS  - 5
SP  - 913
EP  - 920
KW  - 
UR  - https://doi.org/10.1071/CH9940913 
N2  - Two phthalide derivatives (7) and (8) have been prepared from podocarpic acid (1) via directed ortho metallation. The ring-c aromatic 16-oxa-17-oxo androstane analogue (8) was reacted with dimethyl acetylenedicarboxylate to give the 1,4-epoxy decahydrochrysene derivatives (9) and (10). The stereoisomer (10) was aromatized under acidic conditions to give the chrysen-1-ol derivative (11). 
ER  -

