
TY  - JOUR
A1  - Carroll, AR 
A1  - Bowden, BF 
A1  - Coll, JC 
A1  - Hockless, DCR 
A1  - Skelton, BW 
A1  - White, AH 
T1  - Studies of Australian Ascidians. IV. Mollamide, a Cytotoxic Cyclic Heptapeptide From the Compound Ascidian <I>Didemnum molle</I>
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1994
VL  - 47
IS  - 1
SP  - 61
EP  - 69
KW  - 
UR  - https://doi.org/10.1071/CH9940061 
N2  - A new cytotoxic cyclic heptapeptide, mollamide, has been isolated from the compound ascidian Didemnum molle. The structure of mollamide was initially deduced from one-dimensional and two-dimensional n.m.r . experiments at 300 MHz. The structure was confirmed by an X-ray crystallographic study, which showed the relative stereochemistry of the cyclic peptide. Hydrolysis of mollamide , and characterization of the amino acids by derivatization with N&#945; -(5-fluoro-2,4-dinitrophenyl)-L- alaninamide (FDAA; Marfey's reagent) gave the absolute stereochemistry; all constituent amino acids were the L-isomers. Cytotoxicity data are reported. 
ER  -

