
%0 Journal Article
%A Barlin, GB 
%A Nguyen, TMT 
%A Kotecka, B 
%A Rieckmann, KH 
%T Potential Antimalarials. XVII. Di- and Mono-Mannich Bases of 2(and 4)-[2(and 8)-Trifluoromethylquinolin-4-ylamino]phenol
%J Australian Journal of Chemistry
%D 1993/01/01
%V 46
%N 1
%P 21-29
%K 
%R https://doi.org/10.1071/CH9930021
%U https://www.publish.csiro.au/paper/CH9930021 
%X Di- and mono-Mannich base derivatives of 2(and 4)-[2(and 8)-trifluoromethylquinolin-4-ylamino]phenols have been prepared for comparison with the 7-trifluoromethyl isomers in tests for antimalarial activity. The order of activity in in vitro tests against the FC-27 ( chloroquine -sensitive) strain of Plasmodium falciparum was 7-CF3 >> 8-CF3 > 2-CF3. 
