
TY  - JOUR
A1  - Deady, LW 
A1  - Quazi, NH 
T1  - Synthesis of Pyrazino[2,3-c]isoquinolinecarboxylic Acids and Related Compounds
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1992
VL  - 45
IS  - 12
SP  - 2083
EP  - 2087
KW  - 
UR  - https://doi.org/10.1071/CH9922083 
N2  - 1-Methylisoquinoline-3,4-diamine has been synthesized and condensed with &#945;-dicarbonyl compounds to give the fused pyrazine ring. Oxidation of methyl groups gives the 3- and 6-carboxylic acids. Nitration occurs in the benzenoid ring to give the single 10-nitro product, and formation of an unusual 6-trinitromethyl compound is also reported. 
ER  -

