
%0 Journal Article
%A Taylor, RM 
%A Slade, PG 
%A Aldous, GL 
%A Wilding, IR 
%A Siddiqui, O 
%A Whitehouse, MW 
%T Preparation and Properties of a Glycerolatocalcium Complex
%J Australian Journal of Chemistry
%D 1992/07/01
%V 45
%N 7
%P 1179-1185
%K 
%R https://doi.org/10.1071/CH9921179
%U https://www.publish.csiro.au/paper/CH9921179 
%X The synthesis of a glycerolatocalcium complex has been achieved by heating precipitated calcium hydroxide and glycerol to above 180ºC in a microwave oven. The complex has the formula C3H6CaO3, and therefore it appears to have a molecular structure similar to that of the cobalt and zinc analogues. X-Ray powder and single-crystal data are consistent with the complex having an orthorhombic unit cell with a 6.420 ±0.006, b 7.930 ± 0.010, c 8.967 ± 0.010 Å and volume of 456.51 ± 0.69 Å 3. Experiments in vivo (rats) and in vitro were conducted to demonstrate the transdermal permeation that occurred after topical application of this complex. The experiments were aimed at delivering therapeutic amounts of calcium by the transdermal route. 
