
TY  - JOUR
A1  - Hughes, Andrew B. 
A1  - Mackay, Maureen F. 
A1  - Aurelio, Luigi 
T1  - Synthesis and Structural Characterization of <emph type="2">N</emph>-Methyl-DL-glutamic Acid
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 2000
VL  - 53
IS  - 3
SP  - 237
EP  - 240
KW  - X-Ray crystallography; zwitterion; glutamic acid; peptide.
UR  - https://doi.org/10.1071/CH99182 
N2  - The solid-state conformation of racemic N-methylglutamic acid has been defined by single-crystal X-ray crystallography. Orthorhombic crystals belong to the space group Pbca with a 15.219(2), b 10.583(1), c 9.595(1) &#197; and Z 8. The structure was refined to a final R value of 0.049 for the 1285 measured data. In the crystal the molecules adopt a zwitterionic form with protonation having occurred at the amino nitrogen atom. The a-carboxyl is unprotonated with the d-carboxy group retaining a proton. The i.r. spectrum shows absorptions which also are indicative of the amino acid being in the zwitterionic form. Intermolecular H-bonds involving the carboxylate proton and the two protons on the N-atom link the molecules into a three-dimensional network in the crystal. 
ER  -

