
TY  - JOUR
A1  - Rosevear, J 
A1  - Wilshire, JFK 
T1  - Cyclization Reactions in Azole Chemistry: The Reaction of Some Azoles With o-Fluoroacetophenone, o-Fluorobenzaldehyde and o-Fluorobenzophenone
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1991
VL  - 44
IS  - 8
SP  - 1097
EP  - 1114
KW  - 
UR  - https://doi.org/10.1071/CH9911097 
N2  - The reactions of some azoles with o-fluoro-acetophenone , -benzaldehyde and -benzophenone in dimethyl sulfoxide solution in the presence of anhydrous potassium carbonate have been investigated. In addition to the expected substitution products, cyclization reactions frequently occurred to give carbinols in the case of the reactions of o-fluoro-acetophenone and -benzophenone, and cyclic ketones in the case of the reactions with o-fluorobenzaldehyde . Fluoren-9-ol and related carbinols containing heteroaromatic nuclie are readily converted in dimethyl  sulfoxide solution into the corresponding ketones by treatment with anhydrous potassium carbonate. When treated with ethanolic alkali, 2&#8242;-(benzimidazol-1&#8242;-yl) acetophenone undergoes a remarkable transformation to give 1-(2&#82442;-aminophenyl)quinolin-4(1H)-one. 
ER  -

