
TY  - JOUR
A1  - Janowski, WK 
A1  - Prager, RH 
T1  - Potential GABA<sub>B</sub> Receptor Antagonists. IV. Synthesis of 1-[2-Amino-1-(4-chlorophenyl)ethyl]-3-oxo-1,3-dihydro-isobenzofuran-1-yl phosphonic Acid
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1991
VL  - 44
IS  - 3
SP  - 477
EP  - 480
KW  - 
UR  - https://doi.org/10.1071/CH9910477 
N2  - The diastereoselective addition of dimethyl 3-oxo-1,3-hydroisobenzofuran-1-ylphosphonate to nitrostyrene and p- chloronitrostyrene is reported, as is the subsequent conversion of the Michael adducts into 1-[2-amino-1-phenylethyl]-3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid, and 1-[2-amino-1-(4-chlorophenyl)ethyl]-3-oxo-1,3 dihydroisobenzofuran-1-ylphosphonic acid respectively. 
ER  -

