
%0 Journal Article
%A Sandow, Melissa 
%A May, Bruce L. 
%A Clements, Philip 
%A Easton, Christopher J. 
%A Lincoln, Stephen F. 
%T Complexes of 6<emph type="7">A</emph>-(2-Aminoethylamino)-6<emph type="7">A</emph>-deoxy-b-cyclodextrin and 6<emph type="7">A</emph>-[Bis(carboxylatomethyl)amino]-6<emph type="7">A</emph>-deoxy-b-cyclodextrin with (<emph type="2">R</emph>)- and (<emph type="2">S</emph>)-Tryptophanate and (<emph type="2">R</emph>)- and (<emph type="2">S</emph>)-Phenylalaninate in Aqueous Solution. A pH Titrimetric and N.M.R. Spectroscopic Study
%J Australian Journal of Chemistry
%D 2000/03/14
%V 52
%N 12
%P 1143-1150
%K 
%R https://doi.org/10.1071/CH99102
%U https://www.publish.csiro.au/paper/CH99102 
%X The 1 : 1 host&#8211;guest complexes formed by 6A-(2-aminoethylamino)-6A-deoxy-&#946;-cyclodextrin and (R)- and (S)-tryptophanate are characterized by log(K/dm3 mol&#8211;1) = 4.83&#177;0.02 and 4.72&#177;0.03, respectively, and for those formed with (R)- and (S)-phenylalaninate log(K/dm3 mol&#8211;1) = 3.82&#177;0.05 and 4.12&#177;0.02, respectively, in aqueous solution at 298.2 K and I = 0.10 mol dm&#8211;3 (NaClO4), where K is the stability constant. The corresponding values for the analogous complexes formed by 6A-&#91;bis(carboxylatomethyl)amino&#93;-6A-deoxy-&#946;-cyclodextrin are 3.4&#177;0.1, 3.3&#177;0.1, 4.02&#177;0.06 and 4.00&#177;0.06, respectively. Host&#8211;guest complexes are also formed by the monoprotonated substituted &#946;-cyclodextrins. 1H n.m.r. spectroscopy (ROESY) indicates that the guests are complexed with their indole and phenyl entities inside the annuli of the substituted &#946;-cyclodextrin hosts. 
