
TY  - JOUR
A1  - Brimble, Margaret A. 
A1  - Gorsuch, Stephen 
T1  - Deprotonation and Alkylation of 2-Methyl-4,5,6,7-tetrahydro-3<emph type="2">H</emph>-azepine
JF  - Australian Journal of Chemistry
JO  - Aust. J. Chem.
Y1  - 1999
VL  - 52
IS  - 10
SP  - 965
EP  - 970
KW  - 
UR  - https://doi.org/10.1071/CH99094 
N2  - The deprotonation of 2-methyl-4,5,6,7-tetrahydro-3H-azepine (5) using lithium diisopropylamide was effected at &#8722;30&#176;C in tetrahydrofuran. Addition of deuterium oxide resulted in &#62;95% incorporation of deuterium at the exocyclic position. Addition of a range of electrophiles to the organolithium species afforded moderate yields of the alkylation products wherein substitution at the exocyclic position had occurred. 
ER  -

